“…Repeated urine examinations for white cells and organisms are essential in that both may be present intermittently, or even not at all, in latent infections. In this circumstance, pathological increases of white cell excretion rates may be evoked by injections of pyrogen or prednisolone (Little and De Wardener, 1962;Katz et al, 1962) or iron sorbitol citric acid (Devi et al, 1967). In its fulminating bilateral form, acute pyelonephritis may cause renal failure (Kleeman et al, 1960).…”