The preferred technique for knee synovium biopsy and synovial fluid arthrocentesis

Abstract

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Biomarkers in cartilage repair and osteoarthritis

“…LC-MS is already a well-developed technique to identify protein biomarkers in any type of tissue or disease. In combination with a potential biopsy tool, which can already be used preoperatively or in outpatient clinic 373 , protein analysis might be able to predict a patients clinical outcome after surgery or help determining which cartilage repair treatment should be conducted. Whereas lipids are a very interesting type of molecules to investigate and the IPFP is full of them, a lot more is known about the relation of proteins in cartilage repair and OA development 374 .…”