2000
DOI: 10.1016/s0016-5107(00)70362-2
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The prevalence, anatomic distribution, and diagnosis of colonic causes of chronic diarrhea

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Cited by 161 publications
(117 citation statements)
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“…Mucosal biopsies are recommended even when the endoscopic appearance is normal. Th e diagnostic yield of colonoscopy in patients ranges from 7 to 32%, with IBD and microscopic colitis being the most common diagnoses (164)(165)(166)(167)(168)(169). It has also been seen that colonoscopy yields a noninfectious diagnosis more oft en than upper endoscopy (170)(171)(172).…”
Section: Th E Evidence Does Not Support Empiric Anti-microbial Therapymentioning
confidence: 99%
“…Mucosal biopsies are recommended even when the endoscopic appearance is normal. Th e diagnostic yield of colonoscopy in patients ranges from 7 to 32%, with IBD and microscopic colitis being the most common diagnoses (164)(165)(166)(167)(168)(169). It has also been seen that colonoscopy yields a noninfectious diagnosis more oft en than upper endoscopy (170)(171)(172).…”
Section: Th E Evidence Does Not Support Empiric Anti-microbial Therapymentioning
confidence: 99%
“…Collagenous colitis (CC) differs from lymphocytic colitis (LC) in that it presents a sub-epithelial collagen band adjacent to the basal membrane, whereas the hallmark of LC is a dense lymphocytic infiltration in the epithelium. The condition is commoner in women, 22 is a frequent cause of an altered bowel habit towards looser stools, 23,24 and is often accompanied by abdominal pain. [25][26][27] The incidence of MC has been reported as 2.6 to 21.0 Kamp et al…”
Section: Introductionmentioning
confidence: 99%
“…These two forms of microscopic colitis are being diagnosed with increasing frequency; they now account for 10% of cases evaluated for chronic nonbloody diarrhea that are not associated with human immunodeficiency virus (HIV) infection at tertiary medical centers. 5 Since the etiology of these conditions is unknown, therapy has been largely empiric. Furthermore, the natural history of these entities has not been well defined.…”
mentioning
confidence: 99%