The prevalence, mortality rate and functional outcome of intracerebral hemorrhage according to age sex and ethnic group in the state of Qatar

Saqqur, Maher; Salam, Abdul; Ayyad, Ali; Akhtar, Naveed; Ali, Musab; Khan, Adnan; Imam, Yahya; Joseph, Sujatha; Jerdi, Salman Al; Shuaib, Ashfaq

doi:10.1016/j.clineuro.2020.106255

Cited by 11 publications

(13 citation statements)

References 24 publications

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“…In terms of age, previous studies have shown that mortality after ICH increases with age (20-49 years: 16.5%; ≥70 years: 23.9%) (Saqqur et al, 2020). The risk of in-hospital death in patients with ICH ≥65 years old was increased in both men and women compared to < 65 years old .…”

Section: Sex and Age In Previous Studiesmentioning

confidence: 89%

“…In this study, the in‐hospital mortality rate for patients with ICH was 2.1%, much lower than the 30‐40% seen in previous studies. This may be related to the Chinese government's efforts to promote public education and primary stroke prevention, the age‐standardized mortality rate for patients with ICH decreased by 48.1% compared to the previous (Wang et al., 2022 ). At the same time, the data set is mainly from second‐ and third‐level hospitals, which may underestimate the mortality of ICH patients.…”

Section: Discussionmentioning

confidence: 99%

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Association of sex and age with in‐hospital mortality and complications of patients with intracerebral hemorrhage: A study from the Chinese Stroke Center Alliance

Lü

Cao

et al. 2022

Brain and Behavior

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Background and purpose:The impact of sex and age on prognosis in patients with intracerebral hemorrhage (ICH) in the Chinese population remains unclear. Our study aimed to investigate the relationship between sex and age of Chinese ICH patients and adverse prognosis. Methods:We used the Chinese Stroke Center Alliance database with in-hospital mortality as the primary outcome and hospital complications as the secondary outcome.Patients were divided into four groups by sex and age. Logistic regression analyses were performed to assess the association between sex and age and the prognosis of ICH patients. Results:We enrolled 60,911 ICH patients, including 22,284 young and middle-aged males, 15,651 older males, 11,948 young and middle-aged females, and 11,028 older females. After adjusting for variables, older male patients had a higher mortality rate (OR = 1.21, 95% CI 1.01-1.45), combined with more frequent hematoma expansion (OR = 1.14, 95% CI 1.03-1.26), pneumonia (OR = 1.91, 95% CI 1.81-2.03), and hydrocephalus (OR = 1.28, 95% CI 1.04-1.59). Young and middle-aged female patients had a lower mortality rate (OR = 0.74, 95% CI 0.58-0.95) and less frequent combined pneumonia (OR = 0.81, 95% CI 0.75-0.87). In-hospital mortality was not significantly different in older females compared with young and middle-aged males, but the odds of deep vein thrombosis, swallowing disorders, urinary tract infections, and gastrointestinal bleeding were significantly higher. Conclusion:Among young and middle-aged patients, females are related to a lower in-hospital mortality rate from ICH. Older patients are at an increased risk of ICH complications, with higher in-hospital mortality in older men.

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Section: Sex and Age In Previous Studiesmentioning

confidence: 89%

Section: Discussionmentioning

confidence: 99%

Association of sex and age with in‐hospital mortality and complications of patients with intracerebral hemorrhage: A study from the Chinese Stroke Center Alliance

Lü

Cao

et al. 2022

Brain and Behavior

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“…There are a few studies e documenting outcomes in ICH from ethnic communities. These include studies on the clinical course of ICH from Qatar (16,17) Pakistan (18), Africa (19), Saudi Arabia (20), Hong Kong (21), Philippine (22), China (23), India (24), and Singapore (25). The number of patients in most such series is small (19)(20)(21)(22) or the information collected retrospectively (18,21,22,25).…”

Section: Discussionmentioning

confidence: 99%

“…Internationally, ICH incidence is substantially higher in low-income countries and comprises ≈ 18% of all strokes (2)(3)(4). There are a few reports outlining prognosis of ICH from low resource countries (14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25)). The number of patients in such series are small 19,20,21,22,24), and the information collected retrospectively (18,22,23) making prediction modelling difficult to study.…”

Section: Introductionmentioning

confidence: 99%

Short-term Functional Outcomes of Patients with acute intracerebral hemorrhage in the Native and Expatriate Population

Akhtar,

Kate,

Kamran

et al. 2023

Preprint

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Objectives: Functional outcomes in patients with intracerebral hemorrhage (ICH) have not been well characterized in the Middle East and North Africa Region. We report the 30 and 90-day clinical outcomes in the native and expatriate of Qatar with ICH. Methods: We evaluated the Glasgow Coma Scale (GCS), NIHSS, and imaging in the Qatar Stroke Registry (2013-22). The outcome measures were a modified Rankin Scale (mRS) at 90 days and mortality at 30 and 90 days. Unfavourable outcome was defined as mRS of 4-6. We performed non-parametric ROC analyses to measure the concordance index (C-index) to assess the goodness-of-fit of ICH score for predicting 30 day and 90-day mortality and functional outcome. Results: 1660 patients (median age of 49 (41.5-58) years; male 83.1%, expatriates 77.5%) with ICH, including supratentorial deep in 65.2%, cortical in 16.2%, infratentorial 16% and primary intraventricular in 2.5% were studied. The median baseline ICH volume was 7.5 (3.2-15.8) ml. An unfavorable outcome was seen in 673 (40.5%) patients at 90 days. Mortality at 30 days and 90 days was 10.4% and 15.1%. Increasing age (OR (95% CI), 1.02 (1.00-1.03)), lower GCS (0.77 (0.73-0.80)), prior use of antiplatelet medications (1.82 (1.19-2.08)), higher ICH volume (1.03 (1.02-1.04)), and presence of any intraventricular hemorrhage (1.57(1.19-2.08)), were associated with unfavorable outcome. Conclusions: In this relatively younger ICH cohort more than 75% were expatriates, had smaller ICH volume and had better functional outcomes. Prognostic scoring systems may have to be modified in this population to avoid early withdrawal of care.

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“…In an aging society, the fatality and disability rates of stroke in the elderly are estimated to be more than 30%, which brings a huge economic pressure and spiritual burden [ 1 , 2 ]. Due to the lack of professional neurologists and magnetic resonance angiography (MRA) examination facilities, most community hospitals cannot quickly and accurately assess the condition of elderly stroke patients [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

Association between the Triglyceride-Glucose Index and the Risk of Large Artery Atherosclerotic Stroke

Jiang

Zhang

et al. 2022

International Journal of Clinical Practice

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The aim of this study is to evaluate the value of the triglyceride-glucose (TyG) index and the risk of large artery atherosclerotic (LAA) stroke. Information on general demographic and clinical characteristics, magnetic resonance angiography (MRA) examination, and blood biochemical index determination were obtained. Based on age stratification, three models to evaluate the odds ratio (OR) and the 95% confidence interval (95% CI) were employed to determine the correlation between the TyG index and the risk of LAA stroke. The most effective TyG index threshold in predicting a high risk of LAA stroke was identified using receiver operating characteristic (ROC) curve analysis. Logistic regression verified the association between the risk of LAA stroke and the TyG index. Both with and without age stratification, logistic regression analysis showed that the TyG index was a significant predictor of the occurrence of LAA stroke ( P < 0.05 ). The maximum Youden index for determining a high risk of LAA stroke was found at a TyG index of 4.60. The area under the ROC curve was 0.69 (95% CI: 0.646–0.742, P < 0.05 ), sensitivity was 78.0%, and specificity was 63.4%. An elevated TyG index was remarkably associated with a high risk of LAA stroke.

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The prevalence, mortality rate and functional outcome of intracerebral hemorrhage according to age sex and ethnic group in the state of Qatar

Cited by 11 publications

References 24 publications

Association of sex and age with in‐hospital mortality and complications of patients with intracerebral hemorrhage: A study from the Chinese Stroke Center Alliance

Association of sex and age with in‐hospital mortality and complications of patients with intracerebral hemorrhage: A study from the Chinese Stroke Center Alliance

Short-term Functional Outcomes of Patients with acute intracerebral hemorrhage in the Native and Expatriate Population

Association between the Triglyceride-Glucose Index and the Risk of Large Artery Atherosclerotic Stroke

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