The prognostic importance of objective nutritional indexes in patients with chronic heart failure

Narumi, Takatsune; Arimoto, Takanori; Funayama, Akira; Kadowaki, Shinpei; Otaki, Yoichiro; Nishiyama, Satoshi; Takahashi, Hiroki; Shishido, Tetsuro; Miyashita, Takehiko; Miyamoto, Takuya; Watanabe, Tetsu; Kubota, Isao

doi:10.1016/j.jjcc.2013.05.007

Cited by 215 publications

(214 citation statements)

References 24 publications

Supporting

Mentioning

201

Contrasting

Unclassified

Order By: Relevance

“…Suzuki, et al 9) identified nutritional disturbances in 95% of their HF-affected study population. Narumi, et al 14) noted a malnutrition prevalence of 60-69% in chronic HF patients. Additionally, according to a recent review by Lin, et al 6) , the prevalence of malnutrition is higher in advanced HF, and in acute decompensated HF (75-90%).…”

Section: Discussionmentioning

confidence: 99%

“…Nochioka, et al 13) reported that poor nutritional status was associated with increased incidence of death in HF patients classified as stage B in the AHA/ACC guidelines. Furthermore, Narumi, et al 14) reported that the CONUT score was independently associated with the occurrence of cardiovascular events in chronic HF patients. These studies 9,13,14) support our observation that a higher CONUT score was a significant predictor of in-hospital death in hospitalized HF patients.…”

Section: Discussionmentioning

confidence: 99%

“…The undernutrition prevalence in our study population is comparable to those reported in the above-mentioned studies. 6,9,14) Therefore, supportive therapies should be promptly administered on the assumption that hospitalized HF patients often have undernutrition. Furthermore, as HF and undernutrition can each influence the other, once patients develop severe HF, their nutritional status deteriorates further.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Utility of Nutritional Screening in Predicting Short-Term Prognosis of Heart Failure Patients

et al. 2018

View full text Add to dashboard Cite

SummaryControlling nutritional status (CONUT) uses 2 biochemical parameters (serum albumin and cholesterol level), and 1 immune parameter (total lymphocyte count) to assess nutritional status. This study examined if CONUT could predict the short-term prognosis of heart failure (HF) patients.A total of 482 (57.5%) HF patients from the Ibaraki Cardiovascular Assessment Study-HF (n = 838) were enrolled (298 men, 71.7 ± 13.6 years). Blood samples were collected at admission, and nutritional status was assessed using CONUT. CONUT scores were defined as follows: 0-1, normal; 2-4, light; 5-8, moderate; and 9-12, severe degree of undernutrition. Accordingly, 352 (73%) patients had light-to-severe nutritional disturbances. The logarithmically transformed plasma brain natriuretic peptide (log BNP) concentration was significantly higher in the moderate-severe nutritional disturbance group (2.92 ± 0.42) compared to the normal group (2.72 ± 0.45, P < 0.01). CONUT scores were significantly higher in the in-hospital death patients [4 (3-8), n = 14] compared with patients who were discharged following symptom alleviation [3 (1-5), n = 446, P < 0.05]. With the exception of transferred HF patients (n = 22), logistic regression analysis that incorporated the CONUT score and the log BNP, showed that a higher CONUT score (P = 0.019) and higher log BNP (P = 0.009) were predictors of in-hospital death, and the median duration of hospital stay was 20 days.Our results demonstrate the usefulness of CONUT scores as predictors of short-term prognosis in hospitalized HF patients.(Int Heart J Advance Publication)

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Utility of Nutritional Screening in Predicting Short-Term Prognosis of Heart Failure Patients

et al. 2018

View full text Add to dashboard Cite

show abstract

“…CONUT is an assessment tool to judge nutritional status from serum albumin values, total lymphocyte counts, and total cholesterol blood sampling results [9,10]. Because it does not require an examination or interview, it can be simply and objectively evaluated.…”

Section: Bedriddenmentioning

confidence: 99%

Prognostic Factors for the Survival of Elderly Patients Who Were Hospitalized in the Medical Ward of Our Hospital in Japan

Abe¹

2017

Geriatrics

View full text Add to dashboard Cite

It has been a long time since there were many elderly people in Japan. The medical care and costs for the elderly are enormous, and research to lower the mortality rate of the elderly is needed. We retrospectively investigated the prognostic factors for the survival of elderly patients who were hospitalized in the medical ward of our hospital. In total, 277 patients who were hospitalized between 1 January 2014 and 31 May 2017, were included in the retrospective study. Univariate and multivariate analyses of items (vital signs, laboratory data, and so on) were performed, and significant differences between the survival group and death group were subjected to receiver operating characteristic curve analysis. Serum urea nitrogen levels and serum albumin levels provided a relatively high area under the curve (AUC). However, there was no item for which AUC exceeded 0.70, and setting the cutoff value in this study was difficult. For treating the elderly, it is important to carefully evaluate each patient's prognostic factors, including the demented state, renal function, and nutritional state; personalized treatment of each patient is also important.

show abstract

“…Many studies have reported their usefulness in predicting the prognosis in patients with HF. 4,5,15,20,21) Bonilla, et al 5) assessed patients with chronic HF according to the MNA ® and found that 12.8% of patients were malnourished and 60.2% of patients were at risk of malnutrition, while only 27.0% had normal nutritional status. "At risk of malnutrition" includes the possibility of malnutrition that is necessary to be extracted.…”

mentioning

confidence: 99%

Assessment of Transthyretin Combined With Mini Nutritional Assessment on Admission Provides Useful Prognostic Information in Patients With Acute Decompensated Heart Failure

et al. 2015

View full text Add to dashboard Cite

SummaryDecreased Transthyretin (TTR) can be observed in heart failure patients with malnutrition evaluated by the Mini Nutritional Assessment (MNA). This study investigated whether a combination of different nutritional assessment methods would be useful for assessing prognosis in patients with acute decompensated heart failure (ADHF).This prospective study included 52 patients with ADHF (mean age, 71.1 ± 14.7 years; men 55.8%) who were admitted to our hospital between June 2012 and August 2013. On admission, nutritional status was evaluated according to levels of TTR and the MNA. Of 52 patients, 28 (53.8%) had TTR < 15 mg/dL, 39 (75.0%) had malnutrition or were at risk of malnutrition (MNA score ≤ 23.5), and 21 (40.4%) were categorized into group L (MNA score ≤ 23.5 and TTR < 15 mg/dL). Readmission due to worsening heart failure occurred in 12 patients (23.1%), and there were 4 (7.7%) allcause deaths. The 1-year event-free survival rates in group L and the remaining patients (group O) were 27.7% and 85.6%, respectively (P = 0.001). Using Cox multivariate analysis, group L also had a poorer prognosis (hazard ratio 4.35, 95% confidence interval 1.26-17.74, P = 0.020).MNA revealed that 75% of patients with ADHF had malnutrition or were at risk of malnutrition. The combination of low MNA and low TTR on admission can predict the prognosis of patients with ADHF. (Int Heart J 2015; 56: 226-233)

show abstract

The prognostic importance of objective nutritional indexes in patients with chronic heart failure

Abstract: Malnutrition was common in patients with CHF. Evaluation of nutritional status may provide additional prognostic information in patients with CHF.

Cited by 215 publications

References 24 publications

Utility of Nutritional Screening in Predicting Short-Term Prognosis of Heart Failure Patients

Utility of Nutritional Screening in Predicting Short-Term Prognosis of Heart Failure Patients

Prognostic Factors for the Survival of Elderly Patients Who Were Hospitalized in the Medical Ward of Our Hospital in Japan

Assessment of Transthyretin Combined With Mini Nutritional Assessment on Admission Provides Useful Prognostic Information in Patients With Acute Decompensated Heart Failure

Contact Info

Product

Resources

About