The Prognostic Value of Hematological Parameters in Patients with Pulmonary Embolism

Abstract

Anahtar KelimelerPulmoner Emboli; Beyaz Küre Sayısı; Nötrofil Lenfosit Oranı; Ortalama Trombosit Hacmi Abstract Aim: By analyzing the hemogram values of patients with PE during and following the treatment, the relationships of hematological parameters with response to treatment and prognosis of the disease were investigated. Material and Method: Forty-eight patients, who were hospitalized and treated with the diagnosis of PTE in the Pulmonary Diseases Clinic of our hospital between December 2014 and December 2015, were included in the study. The patients' charts, located in the digital archive system, were analyzed retrospectively and demographic characteristics, clinical evaluations, and their hemogram results during and following the treatment were retrospectively evaluated. Among the hemogram parameters, the values of WBC,NLR and MPV were statistically analyzed. For statistical analysis, SPSS 17.0 software and the Kolmogorov-Smirnov test, Mann-Whitney U test and independent sample t test were used. Results: The average age of the 48 patients included in our study was 62.68, and 27 (56.2%) of them were males. The average duration of hospitalization was 9.2 days. The median values of NLR, MPV, and WBC at the time of diagnosis were 4.82 (3.04-9.32), 10.2 (7.40-11.8), and 9215 (6507.5-13255), respectively. Following treatment, these values were 2.60 (1.82-3.74), 9.3 (7-12.9), and 7265 (6125-8872.5), respectively. It was determined that the NLR, MPV, and WBC values were statistically significantly reduced following treatment (p <0,001). Discussion: Our study suggested that NLR,MPV and WBC can be used as prognostic inflammatory indicators for diagnosing and treating pulmonary embolism.

Association between mean platelet volume and pulmonary embolism: a systematic review and meta-analysis

“…Moreover, MPV could be used for risk stratification of PE and added to the current guidelines [ 48 ] to improve the risk estimation accuracy and increase the survival rate. Additionally, MPV could be used as a marker to estimate the effect of treatment, such as anticoagulant and thrombolytic therapies [ 13 , 49 , 50 ].…”