The progress on porous organic materials for chiral separation

Enantioseparation Membranes: Research Status, Challenges, and Trends

“…At present, the chiral membrane materials which have been widely studied and promising mainly include polymer materials, organic framework materials, and inorganic nanomaterials. [39][40][41][42][43][44]…”

Nanocrystalline Porous Materials for Chiral Separation: Synthesis, Mechanisms, and Applications

“…These molecules participate in a diverse array of biological processes, enabling the frameworks to confer defensive capabilities while concurrently expanding its functional repertoire. Given the deliberate design, synthesis, and selective nature of chiral auxiliaries, this attribute bestows upon PMS a remarkable superiority . Nevertheless, the inhomogeneous dispersion of chiral auxiliaries within the material and its consequential detrimental impact on the crystalline morphology and porosity present formidable challenges that this strategy must confront.…”

“…Given the deliberate design, synthesis, and selective nature of chiral auxiliaries, this attribute bestows upon PMS a remarkable superiority. 13 Nevertheless, the inhomogeneous dispersion of chiral auxiliaries within the material and its consequential detrimental impact on the crystalline morphology and porosity present formidable challenges that this strategy must confront. The induction of chirality from achiral assembly systems remains a highly appealing approach for incorporating chirality into NCPMs.…”

“…Such prominence renders it a veritable “popular” element within these spheres. , Following the notoriety of the thalidomide tragedy during the 1950s and 1960s, the prevalence of chiral drugs across diverse therapeutic classes and their substantial market shares compelled scientists to seek efficacious methods of gaining access to optically pure enantiomers. − Presently, there are three main ways to obtain it, including extraction of natural chiral drugs, asymmetric synthesis, and chiral separation . Notably, chiral separation garners favor owing to its capacity for quantitative yield, environmental compatibility, and heightened atom economy. , Chiral materials have demonstrated significant prowess in stability, separation efficiency, and mechanistic investigations, thereby furnishing the indispensable chiral milieu requisite for effective separations. − This observation finds ample support in the prior utilization of a diverse array of materials, ranging from cyclodextrins (CDs), crown ethers, proteins, DNA, and polysaccharide derivatives to macrocyclic antibiotics . As demand intensifies, chiral materials continue to evolve toward greater functional diversity and universality.…”

High Internal Phase Emulsion for Constructing Chiral Helical Polymer-Based Circularly Polarized Luminescent Porous Materials

“…Porous materials with micro–nano structures have aroused mounting interest as they display promising applications in adsorption/separation, optoelectronics, catalysis, drug delivery/release, together with energy storage, and so on. − On the other hand, the ever-rising significance of chirality is reflected in its universality in nature, from chiral amino acids to proteins and DNA possessing helical structures, as well as higher-level chirality. , By judiciously integrating porous materials with chirality, scientists have explored the chiral-associated uses of the resulting chiral porous materials in asymmetric catalysis, chiral separation, chiral sensing, enantioselective release, and chiral optoelectronics . In this regard, chiral porous materials capable of producing circularly polarized luminescence (CPL) have become a hot research topic in the past few years, ,, because CPL reflects the excited-state information of chiral materials, − thus providing a powerful platform for applications of porous materials in cutting-edge fields such as 3D display, asymmetric photocatalysis, sensing, and information encryption, − which is different from applications such as chiral separation that usually only reflects chiral ground-state information afforded by circular dichroism (CD).…”