The Properties of the Ulcinj Peloid make it Unique Biochemical Laboratory Required for the Treatment of Problematic Skin and Health Care

Potpara, Zorica; Pantović, Snežana; Duborija-Kovačević, Nataša; Tadić, Vanja; Vojinovic, Tanja; Marstijepovic, Nada

doi:10.1177/1934578x1701200620

Cited by 4 publications

(5 citation statements)

References 13 publications

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“…The content of heavy metals is below the standard values adopted by the US EPA (EPA, 2012 ). A comparative analysis of the composition of heavy metals shows that the peloids of Western Kazakhstan have mostly similar content of manganese, zinc, copper, lead, and cadmium with sapropels from Romanian saline lakes (Baricz et al, 2021 ), as well as zinc and lead with peloids from Ulcinj coast, Montenegro (Potpara et al, 2017 ), and San Diego de los Baños Thermal Center, Cuba (Suárez Muñoz et al, 2015 ). Comparing the available data from other countries, the mud of Southern and Western Kazakhstan has a low copper content; however, it has a high cadmium content.…”

Section: Resultsmentioning

confidence: 99%

Chemical composition and physicochemical properties of natural therapeutic mud of Kazakhstan salt lakes: a review

Akimzhanova,

Sabitova,

Mussabayeva

et al. 2024

Environ Geochem Health

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In recent years, interest in natural therapeutic mud has been growing all over the world. This natural product has a positive therapeutic effect on the skin and has fewer side effects on the human body. There are more than 40 thousand salt lakes in Kazakhstan. Most of them have natural mud sources, the potential of which has not yet been fully explored. The review presents an analysis of the available information on the physical and chemical properties of the main sources of natural mud from salt lakes in Kazakhstan and Kazakh sanatoriums that use natural mud in the treatment. All available publications, presenting the systematic studies, were used for data analysis. A comparative analysis of the mineralization of water, brine, and silt in one reservoir shows that the mineralization of water is not always the least. The available data indicate a point and partial nature of peloid studies, e.g., inorganic composition of natural muds from Western and Southern Kazakhstan is well described in the literature. In turn, there is a lack of these data from Northern and Eastern Kazakhstan. Studies of peloids in these regions seem to be a promising direction of the future research for both local and world scientists. What is more, there is also a big gap in the analysis of organic matter of muds from the Kazakh lakes. Comparing the state of the art, i.e., the studies from other parts of Asia and Europe, the identification of the organic part of muds is another desirable direction as a potential source of biologically active compounds of natural origin.

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Section: Resultsmentioning

confidence: 99%

Chemical composition and physicochemical properties of natural therapeutic mud of Kazakhstan salt lakes: a review

Akimzhanova,

Sabitova,

Mussabayeva

et al. 2024

Environ Geochem Health

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“…Sulfate ions, together with chloride ions and sodium ions, have an antioxidant and anti-inflammatory effect in the treatment of atopic dermatitis and psoriasis (Tsoureli-Nikita et al, 2002). It is known that sodium ions increase skin permeability, promote moisture retention, activate the ion transport system through the cell membrane, and participate in the elimination of toxins and cell stimulation (Potpara, 2017). Ammonium salts have a keratolytic effect of an anti-allergic and antiinflammatory nature, reducing flaking and facilitating the course of skin diseases such as psoriasis, dermatitis (eczema), etc.…”

Section: Resultsmentioning

confidence: 99%

“…The chemical composition of natural muds, their physical properties, as well as the therapeutic effect are studied by researchers in different countries. A comprehensive physical and chemical study of mud was described, including the determination of pH, granulometry, chemical, and mineralogical composition, organic matter in Romania (Baricz et al, 2021), in Montenegro (Potpara et al, 2017), in Turkey (Odabasi et al, 2007), in Cuba (Martínez-Villegas et al, 2020. The factors influencing the formation of the chemical composition and genesis of silt mud include the salt composition of the brine of the reservoir, soil, and organic matter of plant and animal origin.…”

Section: с уважением благотворительный фонд «халык»!mentioning

confidence: 99%

Chemical Characteristic of the Black and White Mud of the Shoshkaly Lake

Akimzhanova,

Sabitova,

Kairbekov

et al. 2023

SCT

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doctor of chemistry, professor, academician of NAS RK, president of NAS RK, general director of JSC "Institute of fuel, catalysis and electrochemistry named after D.V. Sokolsky (Almaty, Kazakhstan) H = 4 Editorial board: ADEKENOV Sergazy Mynzhasarovich (deputy editor-in-chief) doctor of chemical sciences, professor, academician of NAS RK, director of the international Scientific and production holding «Phytochemistry» (Karaganda, Kazakhstan) H = 11 AGABEKOV Vladimir Enokovich (deputy editor-in-chief), doctor of chemistry, professor, academician of NAS of Belarus, honorary director of the Institute of Chemistry of new materials (Minsk, Belarus) H = 13 STRNAD Miroslav, head of the laboratory of the institute of Experimental Botany of the Czech academy of sciences, professor (Olomouc, Czech Republic) H = 66 BURKITBAYEV Mukhambetkali, doctor of chemistry, professor, academician of NAS RK, first vice-rector of al-Farabi KazNU (Almaty, Kazakhstan) H = 11 HOHMANN Judith, head of the department of pharmacognosy, faculty of Pharmacy, university of Szeged, director of the interdisciplinary center for Life sciences (Szeged, ungary) H = 38 ROSS Samir, Ph.D, professor, school of Pharmacy, national center for scientific research of Herbal Products, University of Mississippi (Oxford, USA) H = 35 KHUTORYANSKY Vitaly, Ph.D, pharmacist, professor at the University of Reading (Reading, England) H = 40 TELTAYEV Bagdat Burkhanbayuly, doctor of technical sciences, professor, corresponding member of NAS RK, ministry of Industry and infrastructure development of the Republic of Kazakhstan (Almaty, Kazakhstan) H = 13 PHARUK Asana Dar, professor at Hamdard al-Majid college of Oriental medicine. faculty of Oriental medicine, Hamdard university (Karachi, Pakistan) H = 21 FAZYLOV Serik Drakhmetovich, doctor of chemistry, professor, academician of NAS RK, deputy director for institute of Organic synthesis and coal chemistry (Karaganda, Kazakhstan) H = 6 ZHOROBEKOVA Sharipa Zhorobekovna, doctor of chemistry, professor, academician of NAS of Kyrgyzstan, Institute of Chemistry and chemical technology of NAS KR (Bishkek, Kyrgyzstan) H = 4 KHALIKOV Jurabay Khalikovich, doctor of chemistry, professor, academician of the academy of sciences of tajikistan, institute of Chemistry named after V.I. Nikitin AS RT (Tajikistan) H = 6 FARZALIEV Vagif Medzhid ogly, doctor of chemistry, professor, academician of NAS of Azerbaijan (Azerbaijan) H = 13 GARELIK Hemda, PhD in chemistry, president of the department of Chemistry and Environment of the International Union of Pure and Applied Chemistry (London, England) H = 15 News of the National Academy of Sciences of the Republic of Kazakhstan. Series of chemistry and technology.

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“…Although the official guidelines for the treatment of patients suffering from acne (Corcoran et al, 2021) do not recognize the importance of cosmeutics such as those used in our study, the results of the application of Peloderm in our subjects are promising. The assumed mechanism of action of the preparation is reduced secretion of sebum and the formation of comedones and acne, as well as antimicrobial and anti-inflammatory effects.All the mentioned effects can be attributed to the chemical ingredients of peloids (Potpara et al, 2017) and extracts of medicinal plants.The presence of silicate algae of the genus Pinullaria in the Ulcinj peloid can be an explanation for the photoprotective effect of Peloderm.I n addition, the presence of bioactive molecules (pantothenic acid, alginic acid, methionine, histidine) in algae contributes to the regulation of moisture and the improvement of epithelization of rough, dry and wrinkled skin (Berthon et al, 2017).…”

Section: Discussionmentioning

confidence: 99%

“…The coast of the Adriatic Sea is rich in peloids, and the object of our interest is the peloid from Ulcinj (south of Montenegro). Its composition, physico-chemical characteristics, antimicrobial activity and other important characteristics were the subject of our previous research (Potpara et al, 2017).…”

Section: Introductionmentioning

confidence: 99%

Peloid-based cosmeutics is effective in the treatment of acnotic skin - prospective study from Montenegro

Potpara,

Pantovic,

Zecevic

2024

Preprint

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Introduction: Among skin diseases, acne represents a special therapeutic challenge because it affects the younger population and significantly affects the quality of life.The chemical composition and biological profile of peloid from Ulcinj (Montenegro) was the subject of our previous research, and the combination of that peloid and medicinal plant tinctures made Peloderm, whose effectiveness in the treatment of acne is tested in this study. Materials and Methods: A prospective study included 140 subjects diagnosed with acne. They were divided in two groups: Peloderm-treated cohort and Emuslion-treated cohort. The FDA-IGA scale was used to monitor the effectiveness of the treatment.Eighteen-months follow up protocol was applied. Results: There were significant differences within the examined groups, namely in part of previous antibiotic therapy, body mass index, alcohol consumption and the presence of stress.FDA-IGA score decreases in both cohorts, but more significantly in Peloderm-cohort. Final FDA-IGA score is significantly lower in Peloderm-cohort. Discussion and Conclusion: Despite official guidelines not recognizing cosmeuticals in acne treatment, Peloderm showed promising results. The formulation's assumed mechanisms of action include reduced sebum secretion, antimicrobial, and anti-inflammatory effects, attributed to peloid and medicinal plant ingredients. Further research are needed.

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The Properties of the Ulcinj Peloid make it Unique Biochemical Laboratory Required for the Treatment of Problematic Skin and Health Care

Cited by 4 publications

References 13 publications

Chemical composition and physicochemical properties of natural therapeutic mud of Kazakhstan salt lakes: a review

Chemical composition and physicochemical properties of natural therapeutic mud of Kazakhstan salt lakes: a review

Chemical Characteristic of the Black and White Mud of the Shoshkaly Lake

Peloid-based cosmeutics is effective in the treatment of acnotic skin - prospective study from Montenegro

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