The Protective Effect of Selenium on Oxidative Stress Induced by Waterpipe (Narghile) Smoke in Lungs and Liver of Mice

Charab, Mohamad A.; Abouzeinab, Noura S.; Moustafa, Mohamed E.

doi:10.1007/s12011-016-0737-9

Cited by 28 publications

(12 citation statements)

References 35 publications

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“…The size, shape and tobacco used in the nargile vary in different regions (7). The most commonly used form of nargile nowadays consists of the head, body, bowl (usually made out of glass), hose, and mouthpiece (7)(8)(9).…”

Section: Introductionmentioning

confidence: 99%

Factors Influencing Hookah Smoking in High School Students

Vapljanin¹,

Kočović²,

Milosavljević³

et al. 2018

Acta Facultatis Medicae Naissensis

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S U M M A R YIn recent years, the prevalence of hookah smoking has increased worldwide, particularly in young people, which may have potentially serious consequences for their health. The aim of this study was to examine the factors associated with the consumption of hookah by high school students.The present study was conducted in the city of Novi Pazar, and students aged 17-19 years attending the following high schools were included: Medical School, Grammar School, Economic-Commerce School and Catering School. The study was designed as a case-control study. The cases were students who consumed nargile, while the control group consisted of students who had never smoked nargile. A special questionnaire was constructed for the purpose of this research, which was used to evaluate the opinions of adolescents on the consumption of nargile.Our research included a total of 270 seniors in high schools in Novi Pazar. The average age of the students was 18 years. The most important factors that may contribute to start using nargile were: previous consumption of nargile by older family members, divorced parents, and active smoking of cigarettes by other family members. Most students emphasized that hookah smoking is socially unacceptable form of behavior. Also, hookah smoker were neither more attractive nor popular.Nargile consumption is more common by adolescents whose parents are divorced, as well as by adolescents whose family members are smoking nargile or tobacco. The most common reason for nargile consumption among adolescents is a desire for relaxation.

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Section: Introductionmentioning

confidence: 99%

Factors Influencing Hookah Smoking in High School Students

Vapljanin¹,

Kočović²,

Milosavljević³

et al. 2018

Acta Facultatis Medicae Naissensis

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“…Quitting water-pipe smoking significantly lowered the level of AST (p<0.05). These findings suggested that waterpipe smoking induces oxidative damage in the liver 17 . Several studies have reported the pathologic effects of smoking in general on liver enzymes 15 .…”

Section: The Effects Of Water-pipe Smoking On Liver Enzymesmentioning

confidence: 85%

The Effect of Smoking Models on the Serum Liver Enzymes

Ababneh¹,

Shraideh²,

Badran³

2017

IRJPS

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ABSTRACT:Introduction: Smoking has been associated with adverse health effects including cardiovascular system and other body organs. Study objectives:The main objective of the present study is to evaluate the effects of smoking models on the level of liver enzymes. Methods: This experimental study was carried out on 30 male albino rats. Male albino rats (Rattusratas) weighted 50-180 g (6-8 weeks old) were used. Rats were randomly assigned to one of 3 groups (n= 10 per group), group 1 was negative control exposed only to fresh air, groups 2 exposed to the most commonly used cigarette brands in the Jordanian market (red LM cigarettes) as 1 cigarette/rat/day for 30 consecutive days. Rats in groups 3 were exposed to flavored water-pipe coming from the complete burning of 20 g from one of moassal for a period of 30 days one session a day for whole body. A digital smoking machine was used. Liver enzymes, LDH, AST, and ALT were evaluated in study groups. Data obtained were analyzed using SPSS version 20. Results:Liver enzymes were significantly increased as a result of exposure to both smoking models: cigarette smoking and water-pipe smoking. It was interestingly found that smoking cessation restore liver enzymes close to control group. Conclusion: Smoking models can induce liver injury as reflected by increased levels of liver enzymes and this injury is reversible if smoking is quitted.

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“…Mice in the test-group were exposed to waterpipe smoke 4 times every other day for within 8 successive days and in the control-group, the mice received no exposure. The results showed that lipid peroxidation markers malondialdehyde and nitric oxide levels were statistically significantly higher in the lungs and liver of mice in the test-group compared with mice in the control-group (Charab et al, 2016). The study concluded that waterpipe smoke induces oxidative stress in the lungs (Charab et al, 2016).…”

Section: Introductionmentioning

confidence: 95%

“…The results showed that lipid peroxidation markers malondialdehyde and nitric oxide levels were statistically significantly higher in the lungs and liver of mice in the test-group compared with mice in the control-group (Charab et al, 2016). The study concluded that waterpipe smoke induces oxidative stress in the lungs (Charab et al, 2016). Moreover, it has been shown in-vitro that waterpipe smoke (a) impairs endothelial vasodilatory function and repair mechanisms, (b) increases the transcriptional expression of matrix metalloproteinase (MMP)-2 and MMP-9 and an immune response regulator, Toll Like Receptor-4 and (c) contributes in the pathogenesis of COPD by inducing inflammation and impairing cellular growth (Rammah et al, 2012, Shihadeh et al, 2014).…”

Section: Introductionmentioning

confidence: 95%

“…In a recent experimental study on mice, chronic exposure to waterpipe smoke was associated with a statistically significant increase in the number of airway inflammatory cells (Al-Sawalha et al, 2017). In another histological study on mice, Charab et al (2016) assessed the association between waterpipe smoke exposure and oxidative stress in lungs. Mice in the test-group were exposed to waterpipe smoke 4 times every other day for within 8 successive days and in the control-group, the mice received no exposure.…”

Section: Introductionmentioning

confidence: 99%

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Toxicological impact of waterpipe smoking and flavorings in the oral cavity and respiratory system

Javed

ALHarthi

Binshabaib

et al. 2017

Inhalation Toxicology

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Waterpipe smoking (WS), an emerging trend has major health concerns. It is prevalent worldwide as a recreational activity both indoors and outdoors. The aim of this review was to assess the impact of waterpipe smoke on the oral and respiratory system (oral cavity and pulmonary tissues). A number of studies have shown that periodontal health status is compromised in waterpipe smokers compared with non-smokers. Some studies have associated WS with oral premalignant and malignant lesions; however, due to the poor quality of these studies, the presented outcomes should be interpreted with caution. Although cigarette smoking has been considered as a potential risk factor for dental caries; there are no studies in indexed literature that have shown an association to exist between dental caries and WS. Inhaled waterpipe smoke imposes oxidative stress and inflammatory responses, and compromises the ventilatory capacity of the lungs and may lead to an increased risk of decline in lung function. WS may cause oral and pulmonary diseases, such as periodontal disease and chronic obstructive airway disease, respectively. The association between WS and development of dental caries and oral pre-cancer and their relationships with chronic airways disease requires investigations. This review discusses the current evidence of waterpipe smoke effects on the oral health and respiratory system based on basic and clinical science, and provides future directions for research and regulatory science on how WS can affect the oral cavity and the respiratory/pulmonary system.

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The Protective Effect of Selenium on Oxidative Stress Induced by Waterpipe (Narghile) Smoke in Lungs and Liver of Mice

Cited by 28 publications

References 35 publications

Factors Influencing Hookah Smoking in High School Students

Factors Influencing Hookah Smoking in High School Students

The Effect of Smoking Models on the Serum Liver Enzymes

Toxicological impact of waterpipe smoking and flavorings in the oral cavity and respiratory system

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