“…While the authors report that addition of the drug aculeacin A (blocks glucan synthesis) does not lead to ring sliding, Bgs1 is resistant to this drug and thus one cannot conclude if the Bgs1 enzymatic activity is necessary for anchoring the ring (Castro et al, 1995;Martins et al, 2011). Bgs1 has been reported to cooperate with Paxillin Pxl1 and Cdc15 to maintain ring integrity and to Martin-Cuadrado et al (2003), Wang et al (2002), Garcia et al (2005), Sipiczki et al (2014), Martin-Cuadrado et al (2008), Wang et al (2003;2015), Perez et al (2015), Santos et al (2005), Munoz et al (2014), Villalobos-Duno et al (2013), Nakano et al (2003) promote septum synthesis (Cortes et al, 2015). Similar to cdc15 and bgs1 mutants, pxl1 mutants also show ring sliding defects (Cortes et al, 2015).…”