The Rapid and Practical Route to Cu@PCR Sensor: Modification of Copper Nanoparticles Upon Conducting Polymer for a Sensitive Non‐Enzymatic Glucose Sensor

Abstract

In this work, rapid, sensitive, practical, and economical strategy for non‐enzymatic glucose sensor has been reported based on a modification of copper nanoparticles upon conducting polymer with high surface area (Cu@PCR). Firstly, PCR conducting polymer electrode (PCR) has been successfully fabricated by electrochemical polymerization of a specially synthesized and characterized star‐shaped carbazole derivative. Then copper nanoparticles have been successfully electrodeposited on the PCR as a practical method with cyclic voltammetry. The morphologies of the synthesized materials have been characterized by scanning electron microscopy (SEM) and energy‐dispersive spectroscopy (EDS) measurements. The Cu@PCR sensor platform has been displayed a synergistic effect of high catalytical properties of copper nanoparticles and high electroactive properties of PCR towards the glucose oxidation in alkaline medium. The Cu@PCR sensor platform has shown high sensitivity of 847 μAmM−1cm−2, good stability (10 weeks), a low detection limit of 0.043 μM, and a fast response of 3 s for the non‐enzymatic electrochemical detection of glucose. This organic−inorganic hybrid composite sensor is a promising candidate for the fabrication of a highly sensitive and rapid glucose‐sensing with the simple preparation procedure and use of a low‐cost precursor.

Recent Advances in Metal–Organic Frameworks (MOFs) and Their Composites for Non-Enzymatic Electrochemical Glucose Sensors

“…Conductive polymers have been used in the field of electrochemical sensing because of their excellent electrical performance [ 158 ]. Among them, conducting polypyrrole (PPy) has been widely used in a variety of non-enzymatic glucose sensing nanocomposites [ 159 ].…”

In Situ Electrochemical Production of Metal‐organic Hybrid Composite Film from Nickel Containing Polyoxometalate and 3,4‐Ethylenedioxy‐thiophene for Sensor Application

“…Among these materials, metal‐based CPs have been used in application of recent developments. Especially, nickel [17, 18], gold [19–22] or copper based [23, 24] CPs have been used to improve the performance of glucose sensor. For example, biomimetic‐composite consisting of nickel nanoparticles polypyrrole has been used as nonenzymatic detection of glucose with fast response, acceptable precision and excellent stability [25].…”