The Rare of the Rarest: Placental Site Trophoblastic Tumor, Epithelioid Trophoblastic Tumor, Atypical Placental Site Nodule

Abstract

Background ETT and PSTT are two of the rarest GTN that share certain features at diagnosis and management. APSN is a relatively new entity considered as a premalignant lesion. Objectives and Methods The aim of this review is to summarize the main characteristics of each of these entities, their diagnostic features and their treatment’s standard of care including fertility sparing treatments. Outcome A thorough review of ETT, PSTT and APSN. Conclusions The reader will gain an insight view of these rare tumors arising from the intermediate trophoblast.