The Rationale for Diagnostic and Treatment Tactics in Patients With Neuroendocrine Tumors of the Small Intestine

Abstract

The OBJECTIVE of the study was to clarify the rational program of diagnosis and choice of treatment tactics for patients with neuroendocrine tumors (NET) of the small intestine, taking into account their clinical and morphological characteristics. MATERIAL AND METHODS. We studied the results of examination and treatment of 39 patients. RESULTS. CT is the main method of topical diagnosis, the sensitivity of which in the detection of NET of the small intestine is 96.4 %. Sign of the localization of NET in the small intestine is the tumor conglomerate of its mesentery, which includes diffuse-infiltrative and nodular variant of changes. The diffuse-infiltrative variant of tumor conglomerate is characterized by increased risk of complicated course of tumor process. Cytoreductive surgical treatment allows to increase the survival rate of patients with generalized NET of the small intestine in 1.7 times. CONCLUSION. Treatment of patients with NET of the small intestine should be carried out in specialized medical centers that have the ability to implement a multidisciplinary approach that can significantly increase the duration and quality of life of patients.