This study aimed to examine the difference of tobacco use, health behaviors and family factors according to the daily tobacco use among female adolescents in South Korea using cross-sectional national data. The study used raw data from the 11th Korean Youth Risk Behavior Web-Based Survey that was performed in 2015. Data of a total of 2,006 female students in high school were analyzed using SPSS/WIN 23. Of the girl 27.5% in high school reported current smoker. Approximately 19.2% of the participants were classified as a daily smoker group. In the multinomial logistic analysis, factors associated with daily smoking were mother's smoking habit, facilities of residence, subjective academic achievement and subjective economic status. In order to develop health promotion strategy and education programs, it is expected to consider factors found relevant in this study.