The Relationship between Beverages Consumption and Cognitive Impairment in Middle-Aged and Elderly Chinese Population

Abstract

Some evidence shows that beverage consumption has an impact on cognitive performance. This is a follow-up study of dietary habits and cognitive function in the Chinese middle-aged and elderly population. The objective of this study was to explore the relationship between beverage consumption and cognitive impairment. The source and grouping of the participants can be seen in the previous article, “Study of Diet Habits and Cognitive Function in the Chinese Middle-Aged and Elderly Population: The Association between Folic Acid, B Vitamins, Vitamin D, Coenzyme Q10 Supplementation and Cognitive Ability”. Among 892 participants, one-third (296) completed both Amyloid beta(Aβ)-PET and plasma biomarkers. The results showed that the consumption of beverages (green tea, coffee, pure milk) was a protective factor for cognitive impairment, daily water consumption <1500 mL (especially <500 mL) was a risk factor for cognitive impairment, and the above correlated with baseline cognitive status. The relationship of green tea, coffee, and pure milk consumption with cognitive impairment was related to gender. We also found that among the participants with Aβ deposition, the consumption of pure milk and green tea was associated with low levels of p-Tau-181. In conclusion, the relationship between beverage consumption and cognitive impairment in Chinese middle-aged and elderly adults may be related to baseline cognitive status, gender, and Aβ deposition.

Study on the relationship between berry, grape, red wine consumption and cognitive impairment in middle-aged and elderly people in China

“…The recruitment methods, inclusion and exclusion criteria and ethical review of participants in this study are the same as those in the previous two articles ( 13 , 14 ). The difference is that, on the basis of the previous study, this research added 235 participants, thus we re-conducted a univariate analysis of the Baseline Characteristics of all the participants.…”

“…Similarly in the previous article, the dietary habit questionnaire was used to collect the clinical data of the subjects, including demographic data, basic physical condition, drug history and personal history (smoking habits, drinking habits) ( 13 , 14 ). The difference is that in this study, we collected the fruit and alcohol consumption of middle-aged and elderly people with different cognitive states.…”

“…We conducted medical history inquiry, physical examination, neuropsychological test, laboratory examination (genetic detection such as APOE) and imaging examination (brain MRI, Amyloid β-PET). The evaluation of participants’ cognitive function and the grouping of participants can refer to the previous two articles ( 13 , 14 ).…”

“…The statistical methods used in this study are the same as those in the previous two articles ( 13 , 14 ). Four groups of subjects were divided into three categories: the NC group and the SCD group in Category one, the MCI group and the AD group in Category two, the objective cognitive unimpaired group (the NC group + the SCD group) and the objective cognitive impairment group (the MCI group + the AD group) in Category three.…”