The Relationship Between Biological Aging with Interdisciplinary Health Indicators: A Scoping Review

Abstract

Objectives: This review aims to provide a comprehensive examination of biomarkers and interdisciplinary variables related to aging. Methods: This scoping review included studies which involved adult participants, and which reported on the relationship between any biomarker or biological age with chronological age. Results: After screening, 447 articles met the selection criteria. Results were categorized into 10 distinct categories through an iterative process. Conclusions: This review contributes information regarding the interdisciplinary influences on the rate of aging. Telomere length was the most commonly examined biomarker, and Horvath's 353-CpG Pan-Tissue clock was the most common clock, with both demonstrating a strong and consistent relationship with chronological age. The interdisciplinary variables demonstrated relationships with biological aging with varying strengths and consistencies.