The relationship between blood lead level with iron status and hemopoietic parameters in smoker and non-smoker workers at lead battery factory

Sadeghi, Hamid Reza; Ghomashlooyan, Mohsen; Azami, Mehdi; Ghalesefidi, Maryam Jamshidian

doi:10.1007/s00580-014-2041-4

Cited by 3 publications

(2 citation statements)

References 16 publications

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“…All reviewed articles ( 18 ) were cross-sectional ( 10 , 11 , 18 – 33 ) study designs. Depending on the country distribution of the studies, nine studies were conducted in Iran ( 10 , 18 , 19 , 21 , 22 , 25 , 27 , 28 , 31 ), and six studies were from India ( 23 , 24 , 26 , 30 , 32 , 33 ), 1 study from Egypt ( 20 ), 1 study from Tunisia ( 29 ), and 1 study from Bangladesh ( 11 ) lead battery manufacturing industries illustrated under Table 1 .…”

Section: Resultsmentioning

confidence: 99%

“Blood lead level among battery factory workers in low and middle-income countries: Systematic review and meta-analysis”

Olana

Kumie

Abegaz

2022

Front. Public Health

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IntroductionLead is one of the most health-hazardous causes of acute and chronic poisoning at workplaces. A limited study was conducted on the blood lead concentration among battery factory workers in low and middle-income countries. Therefore, this study will improve workplace health and safety conditions of workers in this sector and serve as baseline data for further studies in this segment of the working setup.ObjectiveThis review aims to identify the pooled mean blood lead level among battery factory workers in low and middle-income countries.MethodsThe search methods considered the following electronic bibliographic databases: google scholar, PubMed, and other gray literature. A funnel plot and Begg test were used to see the publication bias. The heterogeneity of studies was checked using I-square statistics with a cut of point 75% and the Joanna Briggs Institute (JBI) quality assessment tool was applied to ensure the quality of the included articles. A random-effect model was applied to pool the blood lead level intoxication. The sub-group analysis and Meta-regression analysis were conducted by country and year of publication to control heterogeneity and to show variation. We included the articles published from 2000 to 2021 year in the English language.ResultsThrough the search strategies, 135 articles were identified and 43 full-text articles were selected for evaluation, and finally, eighteen (18) articles fit the inclusion criteria. From the 18 studies included in the meta-analysis, the mean pooled blood lead level of workers was 37.996 μg/dl (95% CI: 30.680–45.312) which is higher than the threshold limit value set by American conference of governmental industrial hygienists (20 μg/dl). In subgroup analysis by year in the random effect model, the pooled mean of blood lead level from 2006 to 2011= 43.20 μg/dL (35.91–50.50), 2012–2015 = 37.78 μg/dl (25.23–50.29), and 2016–2020 = 36.53 μg/dl (19.44–53.62).ConclusionsThis review showed that the pooled mean blood lead level of workers exposed to lead battery factories was (37.996 μg/dl) which is above the threshold limit value (20 μg/dl). Therefore, attention should be given by employers, government, and researchers to improve the health of working populations exposed to lead exposure in low and middle-income countries through the provision of occupational health and safety services like periodical medical checkups, treatments, and provision of training and adequate and appropriate personal protective equipment.Systematic review registration: Identifier: CRD42022322827.

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Section: Resultsmentioning

confidence: 99%

“Blood lead level among battery factory workers in low and middle-income countries: Systematic review and meta-analysis”

Olana

Kumie

Abegaz

2022

Front. Public Health

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“…This study showed that respondents who have higher concentration of Pb in blood, have a lower hemoglobin levels. Previous studies also suggest a link between Pb with hemoglobin levels in workers exposed to Pb (Qasim & Baloch 2014;Sadeghi, 2014;Malekirad, 2013). A study by Richard, (2006) showed that exposure to Pb could inhibit heme biosynthesis via coproporphyrinogen enzyme, δ -ALAD and ferrochelatase inhibition.…”

Section: Methodsmentioning

confidence: 95%

The Effects of Lead (Pb) Exposure to Blood Pb Concentration and Hemoglobin Levels in Book Sellers and Street Vendors of Surakarta

Khotijah

Sjarifah

Mahendra

et al. 2017

Kemas

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Anemia is still a public health problem in the world and in Indonesia. WHO (2008) reported more than 75% of anemia in Asia is iron deficiency and 63.5% anemia in Indonesia is caused by lack of nutrition. Previous studies described that lead (Plumbum /Pb) can decrease hemoglobin levels. Sriwedari markets book sellers and Solo Wholesale Centers street vendors are susceptible populations exposed to Pb as a result of motor vehicle exhaust. Approximately 70% of Pb in vehicle exhausts emissions are emitted into the air. This study aimed to analyze the effects of Pb exposure on blood Pb concentration and hemoglobin levels. This study was a quantitative observational analytic study with cross sectional design conducted in 2015-2016 at Sriwedari Market. Samples were 97 respondents obtained through random sampling and Spearman correlation was used for data analysis. Result showed that there were association between Pb exposure in the air and blood Pb levels (p=0,000; r=0,606) and blood Pb levels and hemoglobin levels (p=0,000; r=-0,623)

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Effects of environmental and occupational lead toxicity and its association with iron metabolism

Słota¹,

Wąsik

Stołtny

et al. 2022

Toxicology and Applied Pharmacology

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The relationship between blood lead level with iron status and hemopoietic parameters in smoker and non-smoker workers at lead battery factory

Cited by 3 publications

References 16 publications

“Blood lead level among battery factory workers in low and middle-income countries: Systematic review and meta-analysis”

“Blood lead level among battery factory workers in low and middle-income countries: Systematic review and meta-analysis”

The Effects of Lead (Pb) Exposure to Blood Pb Concentration and Hemoglobin Levels in Book Sellers and Street Vendors of Surakarta

Effects of environmental and occupational lead toxicity and its association with iron metabolism

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