The relationship between Brucella infection and aortic stiffness in children

Abstract

OBJECTIVE In this study, it was aimed to show whether Brucella infection, which causes various cardiovascular complications in children, can lead to an increase in aortic stiffness with a noninvasive method, echocardiography. METHODS Children who were diagnosed with Brucella infection and who had tachycardia, chest pain and murmur that were not related to body temperature increase during the treatment were evaluated cardiologically and had echocardiographic examination, were included in the study. Aortic strain, aortic distensibility measurement results and aortic stiffness index of the patients in the patient and control groups were calculated. RESULTS Our study included 53 cases with a mean age of 11.43±4.13 years in the patient group and 68 cases with a mean age of 10.16±3.61 years in the control group. We found that systolic blood pressure was lower in the patient group than in the control group (p=0.014). In the analysis of laboratory parameters, blood glucose level was found to be significantly higher in the patient group (p=0.001). In the statistical evaluation of aortic strain, aortic stiffness index and aortic distensibility measurement results between the patient and control groups, no statistically significant difference was found between the groups (p=0.287, p=0.784, p=0.208). CONCLUSION In our study, where we tried to show a new parameter that could contribute to the increase in aortic stiffness, the results showed that Brucella infection was not a factor that increased aortic stiffness in the pediatric age group.