The Relationship between Genetic Variability and Seasonal Changes in Vertical Jump Performance in Amateur Soccer Players

Abstract

This study aimed to investigate the longitudinal evolution of vertical jump height in soccer players and its association with their genotypic profiles. The genotypes of 37 soccer players were characterized and the countermovement jump (CMJ) height, concentric mean power, force, and jump strategy were assessed at two time points: at the onset of the regular season (Pre) and at the conclusion of the first half (Mid). AMPD1 (rs17602729), ACE (rs4646994), ACTN3 (rs1815739), CKM (rs8111989), and MLCK (rs2849757 and rs2700352) polymorphisms were genotyped. No significant differences were found between Pre and Mid in concentric power (p = 0.068; d = 0.08) or force (p = 0.258; d = 0.04), while jump height displayed trivial increases (p = 0.046; d = 0.15). Individual analysis revealed that 38% of participants increased the vertical jump height and mean concentric power over the smallest worthwhile change (SWC), while 27% experienced an increased mean concentric force. The positive responders were characterized by a decreased frequency of the AA genotype and an increased frequency of the CA genotype for the c.37885C>A polymorphism of MLCK (p = 0.035), as well as a decreased frequency of the TT genotype of ACTN3 (p = 0.042) and the CC genotype of AMPD1 (p = 0.022). Our findings suggest that genetic analysis could explain some variability in neuromuscular adaptations during the in-season.