The relationship between mean platelet volume and resistant hypertension

Akın, Halil; Bilge, Önder; Yavuz, Bünyamin; Işık, Ferhat

doi:10.1080/10641963.2021.2022686

Cited by 7 publications

(7 citation statements)

References 25 publications

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“…Risk factors for RHT include advanced age, obesity, chronic kidney disease, black race, and diabetes mellitus [4]. In previous studies, MPV values, which are among the hemogram parameters, have been shown to predict adverse cardiovascular events in RHT patients [16]. In our study, the rate of diabetic patients (p = 0.01) and BMI (p = 0.05) were higher in the RHT group.…”

Section: Discussionsupporting

confidence: 47%

Kırmızı hücre dağılım genişliği ile dirençli hipertansiyon arasındaki ilişki

BİLGE

TAŞTAN

Çap

et al. 2022

Turkish Journal of Clinics and Laboratory

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Aim: Erythrocyte distribution width (RDW) is known to be associated with cardiovascular diseases. Patients with resistant hypertension (RHT) have a higher risk of cardiovascular events. In this study, we aimed to evaluate the relationship between RDW and resistant hypertension. Material and Methods:A total of 157 patients, 69 (43%) of them being resistant hyperten-sion, who had 24-hour ambulatory blood pressure measurement (ABPM) were included in this study. RDW and other laboratory parameters were measured after ABPM. Results:The average age in the study population was 57 ± 11, and 77% (121) of the patients were female. Patients were divided into two groups as controlled and RHT. The RDW was significantly higher in the RHT group (14.8±1.4) compared to the CHT group (14.1±1.2); (p=0,02). RDW by multivariable logistic regression analysis (odds ratio [OR]: 1.684, 95%

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Section: Discussionsupporting

confidence: 47%

Kırmızı hücre dağılım genişliği ile dirençli hipertansiyon arasındaki ilişki

BİLGE

TAŞTAN

Çap

et al. 2022

Turkish Journal of Clinics and Laboratory

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“…The presence of a prothrombotic state is a mechanism involved in the pathogenesis of hypertension (4)(5). The relationship between MPV and hypertension has been shown in various studies (1,(5)(6)(7)(8)12,13). Gang et al (7) followed normotensive individuals for about 9 years and reported that high MPV level was associated with an increased incidence of hypertension independent of other risk factors such as age, sex, serum creatinine, waist circumference.…”

Section: Discussionmentioning

confidence: 99%

“…The relationship between MPV and hypertension has been shown in various studies (1,(5)(6)(7)(8)12,13). Gang et al (7) followed normotensive individuals for about 9 years and reported that high MPV level was associated with an increased incidence of hypertension independent of other risk factors such as age, sex, serum creatinine, waist circumference. Mean platelet volume values were found to be higher in hypertensive patients than in normotensives (5,6,13).…”

Section: Discussionmentioning

confidence: 99%

“…An increase in the risk of prothrombosis due to platelet activation is a factor involved in the pathogenesis of hypertension (4)(5). Significant relationships between hypertension and MPV levels have been shown in various studies (1,(5)(6)(7)(8). In addition, it was found that MPV levels were higher in those with target organ damage due to hypertension than in those without (5,6,9).…”

Section: Introductionmentioning

confidence: 99%

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Yeni tanı konulan hipertansif hastalarda antihipertansif ilaç başlanmasının MPV düzeyine etkisi

Kutlugun

EFE

Güven

2022

Osmangazi̇ Journal of Medicine

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Trombosit aktivasyonu hipertansiyon patogenezinde rol oynayan bir faktördür. Ayrıca, trombotik olayların gelişimine ve hipertansiyona bağlı hedef organ hasarına katkıda bulunur. Mean platelet volume, platelet aktivasyonunu gösteren kolay ölçülebilir bir parametredir. Bu çalışmanın amacı, yeni tanı almış hipertansif hastalarda antihipertansif ilaç tedavisine başlandıktan sonra MPV düzeylerinde herhangi bir değişiklik olup olmadığını değerlendirmektir. Antihipertansif ilaç tedavisine başlanan 79 hasta retrospektif olarak değerlendirildi. Hastaların% 24.1'inde mikroalbüminüri vardı. Antihipertansif ilacın başlamasından önceki ve sonraki MPV değerleri (5.8=3.6 ay) istatistiksel olarak karşılaştırıldı. Antihipertansif ilaç tedavisine başlandıktan sonra ortalama MPV değerinde istatistiksel olarak anlamlı azalma saptandı (8.92=1.76 fl'ye karşılık 8.38=1.60 fL, p<0.001). Ortalama MPV değeri mikroalbüminürik grupta normoalbüminürik gruba göre daha yüksekti (9.24=1.10 fLvs. 8.49 = 1.75 fL, p = 0.028). Yeni tanı konulan hipertansif hastalarda antihipertansif ilaç başlanmasını takip eden ilk yıl içinde ortalama MPV düzeyinde anlamlı bir azalma tespit edildi.

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“…* Mann-Whitney U test, # Student's t-test. Te bold values represent statistically signifcant p values (p < 0.05).between resistant and controlled hypertensive individuals and between resistant and normotensive individuals were statistically signifcant (p � 0.008, p < 0.001, respectively)[16]. In a study by Surgit et al, the MPV was 8.97 ± 0.99 fL in individuals with resistant hypertension, 8.46 ± 0.84 fL in patients with controlled hypertension, and 8.17 ± 0.…”

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confidence: 96%

Evaluation of Mean Platelet Volume in Children with Hypertension

Yildiz,

Kizilca

2023

International Journal of Hypertension

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Background. Childhood hypertension, a disease with increasing prevalence, can lead to severe health problems. With the increased pressure on the vascular endothelium in hypertension, lesions in the endothelium result in endothelial activation and a process of inflammation, which causes platelet activation and in the bone marrow the release of platelet precursor cells into the peripheral blood stream. During inflammation, changes in the number and size of platelets are observed. With the release of platelet precursors into the peripheral blood stream due to platelet activation, an increase in mean platelet volume (MPV) is also seen. Aim. Our aim in this study is the evaluation of MPV changes in the hemogram of children suffering from hypertension, a condition causing severe cardiovascular problems. Material and Methods. This research is a descriptive retrospective cross-sectional study. It consists of a patient group diagnosed with hypertension and a control group of children presenting for routine check-ups with no diagnosed hypertension. Demographic characteristics, arterial pressure values, and hemogram parameters have been evaluated. Results. A total of 90 cases were enrolled in the study, including a patient group of 45 cases with hypertension (19 females, 26 males) and a control group of 45 cases (27 females, 18 males). The median age was 15 years in the hypertension group and 13 years in the control group. In the hypertension cases, the thickness of the carotis intima media was statistically significantly greater than in the control group ( p < 0.001). Echocardiographic findings (IVSd, LVDd, LVPWd, IVSs, LVDs, LVPWs, and LV mass) were significantly higher in the hypertension group compared to the control group ( p < 0.001). A statistically significant difference in platelet count and MPV values between the groups was not found ( p = 0.151, p = 0.405, respectively). Conclusion. While MPV is hypothesized to be higher in hypertensive individuals, there was no statistically significant difference between the hypertensive and non-hypertensive groups in this study.

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The relationship between mean platelet volume and resistant hypertension

Cited by 7 publications

References 25 publications

Kırmızı hücre dağılım genişliği ile dirençli hipertansiyon arasındaki ilişki

Kırmızı hücre dağılım genişliği ile dirençli hipertansiyon arasındaki ilişki

Yeni tanı konulan hipertansif hastalarda antihipertansif ilaç başlanmasının MPV düzeyine etkisi

Evaluation of Mean Platelet Volume in Children with Hypertension

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