The relationship between serum level of thyroid hormones, trace elements and antioxidant enzymes in dromedary camel (Camelus dromedarius)

Abstract

Thyroid hormones might be able to regulate the activities of superoxide dismutase (SOD), catalase and glutathione peroxidase (GPX). The role of thyroid hormones in metabolic pathways and antioxidant enzyme activities are well known in many species. Nevertheless, there is no report describing probable relationship between thyroid hormones status, erythrocyte antioxidant enzymes and serum profiles of trace elements. This study was undertaken to investigate the relationship between these parameters in Iranian dromedary camels. Blood samples were taken from the jugular vein of 30 clinically healthy Iranian dromedary camels under aseptic conditions during 6 consecutive days of summer. The serum was analyzed for serum profile of thyroid hormones, trace elements, SOD and GPX activity. There were no significant differences in serum thyroid hormones, serum level of zinc (Zn), copper (Cu), manganese (Mn), iron (Fe), selenium and antioxidant enzymes in different days (P > 0.05). There was a significant negative correlation between SOD and Fe (P < 0.01, r = -493). There was no significant correlation between other parameters. In case of copper deficiency likewise the present study, the copper was used to produce more SOD, so there was a decrease in Fe transportation, and it might be a cause of decrease in Fe amount. On the other hand, a relatively small quantity of Fe is present in tissue myoglobin, catalase, peroxidases, and cytochromes. So it might be another cause of decrease in Fe amount. The explanation for these finding is not possible at this moment and further investigations are needed to interpret these changes.

Physiological response of dromedary camels to road transportation in relation to circulating levels of cortisol, thyroid hormones and some serum biochemical parameters

“…The mean serum basal concentrations of thyroxine (T 4 ) in Iranian dromedary camels were in agreement with the values reported earlier (Nazifi et al 1999(Nazifi et al , 2009Zia-ur-Rahman et al 2007). The mean serum basal concentrations of triiodothyronine (T 3 ) in the serum of Iranian dromedary camels were in agreement with the values reported earlier (Nazifi et al 1999, Nazifi et al 2009), but higher than values reported by other workers (Bengoumi et al 1999) and lower than values reported by Zia-ur-Rahman et al (2007).…”

“…The mean serum basal concentrations of triiodothyronine (T 3 ) in the serum of Iranian dromedary camels were in agreement with the values reported earlier (Nazifi et al 1999, Nazifi et al 2009), but higher than values reported by other workers (Bengoumi et al 1999) and lower than values reported by Zia-ur-Rahman et al (2007). Our results indicated no effect of sex on circulating iodothyronines levels in dromedary camels that is different from results of Bengoumi et al (1999) who showed female dromedaries have lower T 3 and T 4 concentrations.…”

Selenium and copper status of camels in Al-Jouf area (Saudi Arabia)

“…In Morocco, in dromedaries receiving probably a low Se basal diet, the plasma selenium concentration was quite lower, about 21 ng/ml (Bengoumi et al 1998a). Recently, in male adult camels in healthy conditions from Iran, the selenium concentration reported in serum was 12.6 ng/ml only (Nazifi et al 2009). In the United Arab Emirates (UAE), the mean value was 200±90 ng/ml in animals with no Se supplementation (Seboussi et al 2004).…”

Dietary implications on mechanisms of sarcopenia: roles of protein, amino acids and antioxidants

“…Moreover, several trace minerals exist, including copper, iron, manganese, selenium and zinc [113][114][115][116]. These components play important roles by contributing to the antioxidant system as cofactors for antioxidant enzymes.…”