The Relationship between Standard Automated Perimetry and GDx VCC Measurements

Reus, Nicolaas J.; Lemij, Hans G

doi:10.1167/iovs.03-0646

Cited by 114 publications

(88 citation statements)

References 31 publications

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“…Many reports showed that with respect to SLP with fixed compensation (GDx-FCC), the use of variable compensation (GDx-VCC) improves significantly the structure-function relationship 5 and diagnostic ability in glaucomatous eyes. [6][7][8][9][10][11][12][13][14] Moreover, early RNFL thinning in perimetrically unaffected fellow eyes of patients with unilateral glaucoma was detected. 15 However, some eyes had to be discarded from these studies because an atypical pattern of retardation (APR) appeared on the retardation map available in the printout.…”

Section: Introductionmentioning

confidence: 90%

Atypical pattern of retardation on GDx-VCC and its effect on retinal nerve fibre layer evaluation in glaucomatous eyes

Pozzo

Marchesan

Canziani

et al. 2005

Eye

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Section: Introductionmentioning

confidence: 90%

Atypical pattern of retardation on GDx-VCC and its effect on retinal nerve fibre layer evaluation in glaucomatous eyes

Pozzo

Marchesan

Canziani

et al. 2005

Eye

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“…To calculate the mean VF loss in these six areas, the anti-log values at all single test positions were calculated and then averaged. 8,9 For presentation and statistical analyses, these averaged values were converted back to the dB scale. 9 Hood et al 4 suggest that it is important to anti-log SAP values before averaging the values.…”

Section: Vf Testmentioning

confidence: 99%

“…8,9 For presentation and statistical analyses, these averaged values were converted back to the dB scale. 9 Hood et al 4 suggest that it is important to anti-log SAP values before averaging the values. On the basis of the knowledge that underlying ganglion cell number and differential light sensitivity expressed as 1/Lamberts has a linear relationship (r 2 ¼ 0.73), 24 they provided the following rationale for antilogging SAP values before averaging them.…”

Section: Vf Testmentioning

confidence: 99%

“…Significant correlations have been described between glaucomatous structural changes of the optic disc and/or retinal nerve fiber layer (RNFL) and functional changes on VF testing. [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18] Determining whether there is good correlation between localized VF defects and localized RNFL defects may be important in deciding whether glaucomatous progression has occurred and in understanding the pathogenesis of the disease.…”

Section: Introductionmentioning

confidence: 99%

“…This paper, in particular, focuses on the topographic association between specific areas of glaucomatous VF loss and specific locations in the course of the RNFL bundles, and this topographic association can be delineated by structure-function correspondence maps. Many studies 3,4,9,10,13,15,18 have used the Garway-Heath map, 19 which maps VF test point locations to specific regions of the ONH. Weber et al 20 described another structure-function map that correlated VF test points to optic disc margin locations, which were then extrapolated to OCT RNFL defects.…”

Section: Introductionmentioning

confidence: 99%

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Correlation of localized glaucomatous visual field defects and spectral domain optical coherence tomography retinal nerve fiber layer thinning using a modified structure–function map for OCT

Boer

Chen

et al. 2015

Eye

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Purpose To study the correlation between glaucomatous visual field (VF) defects assessed by standard automated perimetry (SAP) and peripapillary retinal nerve fiber layer (RNFL) thinning measured by spectral domain optical coherence tomography (OCT) using a modified OCT-based peripapillary RNFL structure-function map. Patients and methods Perimetric glaucoma patients and age-matched normal control subjects were recruited from a university hospital clinic. All eyes underwent testing with the Spectralis spectral domain OCT and SAP on the same day. An OCT-based correspondence map, which correlated VF areas with peripapillary RNFL sectors was created to evaluate the relationship between glaucomatous RNFL thinning and VF loss in six nerve fiber layer bundle areas. Correlations of RNFL thinning with corresponding VF defects were examined using Spearman rankorder correlations. To demonstrate the association between localized VF defects and RNFL thickness, the theoretical curves were made according to an established log-linear model. The measured RNFL thickness values and VF defects were presented in the same scatterplot for each sector. Results Fifty-six glaucoma patients and 85 normal subjects were included in the study.Significant association between localized VF loss and RNFL thinning was found in corresponding areas. Data from the current study fit well with established log-linear models, which compare RNFL thickness values with VF defects. Conclusion Analysis of RNFL thinning in eyes with localized glaucomatous VF defects showed good structure-function correlation in a new OCT-based structure-function correspondence map.

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Correlation of Retinal Nerve Fiber Layer Measured by Scanning Laser Polarimeter to Visual Field in Ischemic Optic Neuropathy

Danesh‐Meyer

Carroll²,

Ku³

et al. 2006

Arch Ophthalmol

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To evaluate the relationship between retinal nerve fiber layer (RNFL) measurement with scanning laser polarimetry (SLP) and standard automated perimetry (SAP) in nonarteritic anterior ischemic optic neuropathy (NAION). Methods: In this prospective observational case series, all subjects (28 eyes with NAION) underwent SAP and SLP. The RNFL retardation measurements and visual field test points were grouped into 6 corresponding sectors. The contralateral uninvolved eye was used as control. The relationship between RNFL retardation and SAP was evaluated with the Spearman nonparametric technique and linear regression analysis. The main outcome measure was correlation of SLP RNFL parameters and SAP. Results: Global and sectoral SLP parameters showed a significant difference in affected eyes compared with controls. The strongest correlations were seen between mean deviation and number (r=−0.524; P=.004), ellipse modulation (r=0.5026; P =.006), and maximum modulation (r = 0.526; P = .004). Superior sectoral visual field indexes showed a strong correlation with inferior RNFL changes (r = 0.522; PϽ.008). Linear regression confirmed a strong relationship between the superior sectoral visual field indexes and the inferior RNFL. Conclusion: Scanning laser polarimetry was able to identify structural changes of the RNFL globally and in the inferior SLP sector with functional loss in NAION.

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The Relationship between Standard Automated Perimetry and GDx VCC Measurements

Cited by 114 publications

References 31 publications

Atypical pattern of retardation on GDx-VCC and its effect on retinal nerve fibre layer evaluation in glaucomatous eyes

Atypical pattern of retardation on GDx-VCC and its effect on retinal nerve fibre layer evaluation in glaucomatous eyes

Correlation of localized glaucomatous visual field defects and spectral domain optical coherence tomography retinal nerve fiber layer thinning using a modified structure–function map for OCT

Correlation of Retinal Nerve Fiber Layer Measured by Scanning Laser Polarimeter to Visual Field in Ischemic Optic Neuropathy

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