The Relationship Between Vision-related Quality of Life and Visual Function in Glaucoma Patients

Abstract

Purpose:To evaluate the relationship between vision-related quality of life (QOL) as measured by the short-form 11-item Japanese version of the Visual Function Questionnaire (VFQ-J11) and the severity of visual field (VF) defects in patients with glaucoma.Methods:The study included 134 glaucoma patients and 30 normal subjects. VF testing using the Humphrey Field Analyzer was performed to obtain both the VF index (VFI) and MD in both eyes of each glaucoma patient. Binocular integrated VF was constructed for each patient by merging corresponding sensitivity values from monocular VFs, and the correlation between visual function and vision-related QOL was then assessed.Results:A significant relationship was found between QOL and VF in 6 of 7 subscales on the VFQ-J11, and between the composite scores in both the better eye and the worse eye in glaucoma patients. The relationship was stronger in the worse eye than in the better eye. Overall, correlation coefficients of the VFI were higher than those of MD and slightly higher than those of integrated VF in the worse eye.Conclusions:The VFI showed a marginally better correlation than MD. Assessment of VFI in the worse eye may provide useful information regarding vision-related QOL in glaucoma patients.

Oxidative and Anti-Oxidative Stress Markers in Chronic Glaucoma: A Systematic Review and Meta-Analysis

“…This pathology causes significant impact on visual function that may affect the quality of life and work productivity [3,4]. Due to its long time asymptomatic evolution, this disease remains under-diagnosed and the irreversible loss of optic nerve fibers leads to important visual field loss [5].…”

Performance and Safety of a New Ab Interno Gelatin Stent in Refractory Glaucoma at 12 Months

“…common in glaucoma and has been linked to poor outcomes and increased healthcare costs. [1][2][3][4] Considering that glaucoma can lead to irreversible visual impairment and impact quality of life if not properly treated, [5][6][7][8][9][10][11][12][13][14][15][16][17][18] and that the disease incidence rises as the world population ages, [19][20][21][22][23][24][25][26][27] efforts are being deployed to develop longer-term treatments that can alleviate nonadherence. Minimally invasive glaucoma surgery (MIGS) devices, for example, are being investigated because they can potentially lower intraocular pressure (IOP) over several years.…”

The Glaucoma Intensive Treatment Study (GITS), a randomized clinical trial: design, methodology and baseline data

“…The goal for all study eyes was to halt or reduce visual field progression before reaching the VFI value of 50%, an arbitrary limit for serious visual field loss. Papers published after this study was designed have reported reduced visual-related QoL in glaucoma patients with a VFI worse than 50% in the best eye (Peters et al 2015) or in the worse eye (Hirooka et al 2016). A paper by Jones et al 2017 reported that vision-related QoL declined rapidly at MD values below À15 dB in the better eye, which corresponds approximately to VF 50%.…”

“…Another important outcome is quality of life (QoL). The results of two recent studies, the first of patients included in the Early Manifest Glaucoma Trial, supported the arbitrary, albeit widespread, use of a limit at approximately 50% of a full field as an important cut-off from where significant reduction in vision-related QoL could be measured (Peters et al 2015;Hirooka et al 2016).…”