The revised 2014 GINA strategy report

Boulet, Louis‐Philippe; FitzGerald, J Mark; Reddel, Helen K.

doi:10.1097/mcp.0000000000000125

Cited by 121 publications

(117 citation statements)

References 34 publications

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“…The diagnosis and staging process were performed in accordance with the guidelines of Global Initiative for Asthma (GINA) for asthma patients and the Global Initiative for Chronic Obstructive Lung Disease (GOLD) criteria for COPD patients [21,22]. The attacks were initially assessed by emergency medicine and chest diseases research assistants and on-call chest diseases professors in the emergency medical unit.…”

Section: Methodsmentioning

confidence: 99%

To Investigate the Effects of Air Pollution (PM10 and SO2) on the Respiratory Diseases Asthma and Chronic Obstructive Pulmonary Disease

et al. 2017

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OBJECTIVES:Effects of air pollution parameters of sulfur dioxide (SO2) and particulate matter (PM10) values on the respiratory system were investigated. MATERIAL AND METHODS:Data of SO 2 and PM10 were obtained daily for air pollution and classified into two groups: Group I (2006Group I ( -2007, coal burning years and Group II (2008II ( -2009, natural gas+ coal burning. Groups I and II were divided into two subgroups according to the months of combustion as combustible (November-April) and noncombustible (May-October). The number of patients with asthma and chronic obstructive pulmonary disorder (COPD) was recorded between 2006 and 2009. RESULTS:There was no statistically significant difference between Groups I and II for PM10 and SO 2 (p>0.05). Within the years, the values of SO 2 and PM10 were statistically different between the groups defined by month (p<0.01). The number of patients in the combustible and noncombustible subgroups were found to be different for every 4 years, and the numbers of patients with COPD or asthma were not changed through the years. There was a strong correlation between PM10 and COPD (r=0.59, p<0.01) and a weak correlation between PM10 and asthma (r=0.25, p>0.05). A correlation was found between SO 2 and COPD (p<0.01) but not between SO 2 and asthma (p>0.05). The number of visits for COPD and asthma was statistically different between combustible and noncombustible subgroups (X2:58.61, p=0.000; X2:34.55, p=0.000, respectively). The r2 values for SO 2 and PM10 for COPD patients were 17% and 24%, respectively, in contrast to 8% and 5%, respectivley for asthma patients. CONCLUSION:Air pollution is known to increase respiratory disease occurrences. With decrease in the usage of solid fuel, air pollution could be reduced and may be effective in preventing respiratory diseases. KEYWORDS:Air pollution, respiratory system disease, PM10, SO 2 , asthma, COPD INTRODUCTIONInhalation of toxic particles and gases increases epithelial permeability, which is one of natural defense mechanisms of the lungs; decreases mucociliary activity; and depresses macrophage functions. These substances render toxic effects in healthy or unhealthy individuals and can be a component of molecular events that commonly develop [1]. In vitro experimental studies conducted on humans and animals showed that the damages caused increased inflammatory cellular activation (e.g., neutrophils, T lymphocytes, macrophages, and mast cells), increased production of inflammatory cell proteins (cytokines and chemokines), increased oxidative stress with free radical formation [2] (superoxide, hydrogen peroxide, and hydroxyl radicals), and decreased antioxidant enzyme levels (glutathione transferase and superoxide dismutase) [3].Several studies have shown that particulate matter (PM) in the air affect short-and long-term health. In many studies, there is evidence of effects of PM10 and PM2.5 (PM diameter of 10 or 2.5 µm) on asthma and chronic obstructive pulmonary disease (COPD) and on the increased rate of hospitalization [4]. Stud...

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Section: Methodsmentioning

confidence: 99%

To Investigate the Effects of Air Pollution (PM10 and SO2) on the Respiratory Diseases Asthma and Chronic Obstructive Pulmonary Disease

et al. 2017

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“…Canadian and French recommendations proposed the concept of control [3,4], and the National Asthma Education and Prevention Program Expert Panel Report initiated the concept of risk for asthma [5]. However, GINA is globally considered to be the prominent asthma recommendation building on existing knowledge and providing several updates or revisions since it was introduced in 1995 [2,6,7]. GINA 2015 represents a significant advance over the previous iteration, with a more practical approach and an increased appreciation of asthma as a public health problem [8].…”

Section: @Erspublicationsmentioning

confidence: 99%

GINA 2015: the latest iteration of a magnificent journey

Bousquet

Humbert

2015

Eur Respir J

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“…The study was approved by local ethics committee (2014/400 Date:12.15.2014). The subjects over 16 years of age, defined asthma according to Global Initiative for Asthma (GINA) [1] and suspicious of allergic sensitization included in the study. SPT was not performed in patients, especially those taking antihistamines, corticoids, bronchodilators, mast cell stabilizers and immunosuppressive drugs, their medications discontinued two or three weeks before the procedure depending on the medication [5].…”

Section: Methodsmentioning

confidence: 99%

“…Asthma is defined by the history of respiratory symptoms such as wheeze, shortness of breath, chest tightness and cough that vary over time and in intensity, together with variable expiratory airflow limitation [1]. Allergic asthma is the most easily recognised phenotype, which is seen generally in childhood and is associated with a past and or family history of allergic diseases such as eczema, allergic rhinitis, food or drug allergy.…”

Section: Introductionmentioning

confidence: 99%

Skin prick test results of atopic asthmatic subjects in a chest disease clinic in Sanliurfa

Koc¹,

Doğan²,

Doğan³

et al. 2015

Dicle Med J

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ÖZETAmaç: Allerji deri testi atopik hastaların değerlendirilme-sinde sık kullanılmakta ve hızlı sonuç alınabilmektedir. Bu çalışmada amacımız Şanlıurfa'da atopik astımlı hastaların aeroallerjen duyarlılığını değerlendirmektir.Yöntemler: Çalışmada 95 erkek, 162 kadın toplamda 257 atopik astımlı hastanın klinik, demografik verileri ile deri prick testi sonuçları geriye dönük olarak değerlendi-rildi. Bulgular:Yapılan deri prick testinde en sık allerjiye yol açan allerjenler sırasıyla; hamam böceği (%56,8), buğ-day poleni (%53,3), mısır poleni (%47,4), çimen poleni(%36,5), kavak ağacı poleni (%26), ev tozu akarı (%19,4), biber tozu (%16,7) ve kedi tüyü (%15,1) olarak saptandı.Sonuç: Buğday ve mısır polenine yüksek oranda duyarlı-lık, kedi tüyüne ise daha az oranda duyarlılık saptanması tarımla uğraşan ve kedi besleme alışkanlıkları sık olmayan bölgede beklentilerimizi karşılamaktadır.Anahtar kelimeler: Atopi, aeroallerjenler, deri allerji testi ABSTRACT Objective: Skin prick test (SPT) is used widely to determine the allergens in atopic patients. In this study, we aimed to determine the spectrum of aeroallergen sensitivity of atopic asthmatic subjects in Şanlıurfa district. Methods:We evaluated clinical, demographic findings and SPT results of 95 male and 162 female in a total 257 patients who had asthma and allergic symptoms. Results:Most common allergens causing a sensitivity reaction detected in our clinic were as follows; cockroach (56.8%), wheat pollen (53.3%), corn pollen (47.4%), grass pollen (36.5%), poplar tree pollen (26%), house dust mite (19.4%), pepper (16.7%) and cat dander (15.1%). Conclusion:High levels of sensitivity to wheat and corn pollens and relatively low sensitivity levels of cat dander results meet our expectations in the area of agricultural land and where pet ownership is not common.

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The revised 2014 GINA strategy report

Abstract: The GINA 2014 report provides updated and more easily implementable recommendations on optimal asthma management.

Cited by 121 publications

References 34 publications

To Investigate the Effects of Air Pollution (PM10 and SO2) on the Respiratory Diseases Asthma and Chronic Obstructive Pulmonary Disease

To Investigate the Effects of Air Pollution (PM10 and SO2) on the Respiratory Diseases Asthma and Chronic Obstructive Pulmonary Disease

GINA 2015: the latest iteration of a magnificent journey

Skin prick test results of atopic asthmatic subjects in a chest disease clinic in Sanliurfa

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