The role of diarrhoeagenic Escherichia coli in acute diarrhoeal diseases in Bandar-Abbas, Iran

Abstract

Summary.The prevalence of different types of diarrhoea-producing Escherichia coli was measured in 273 patients attending 12 out-patient clinics in Bandar-Abbas, State of Hormozgan, Iran, during March 1984. Enteropathogenic E. coli (EPEC) belonging to 12 different serogroups, of which 0128 and 0126 were the most common, were found in almost 31% of the patients. Enterotoxigenic strains of E. coli (ETEC) were the next most frequent group (21.9%); among these, 36 (60%) strains produced heatstable enterotoxin (ST), 14 (23.3%) strains produced both heat-labile enterotoxin (LT) and ST, and 10 (16.7%) strains produced LT only. The same pattern of toxigenicity was observed among the EPEC isolates. Ten of the 12 serogroups encountered in this study contained toxin producers, amongst which strains producing ST were dominant. Enteroinvasive E. coli (EIEC) strains were not isolated. These findings suggest that enterotoxin-producing E. coli may be an important cause of diarrhoea in this part of Iran.

Diagnosis and prevalence of enteropathogenic bacteria in children less than 5 years of age with acute diarrhea in Tehran children's hospitals

“…Regardless of the difference in bacterial pattern of acute diarrhea, this difference can be due to technical problems in sampling and isolation of Campylobacter strains. 18,28 Yersinia was not found in this study however, its rate in children with diarrhea was 2.7% in another report. 29 Diarrheagenic E. coli is among the most prevalent causative agents in acute diarrhea in Iran, particularly in children.…”

“…4,11e16 Shigella is an important pathogen in developing countries and one of the most important etiological agents of acute diarrhea in Iran, especially in children. 17,18 In this study Shigella spp. was isolated in 148 (13.5%) of all patients, similar to another study conducted in Iran 17 but sensibly higher than previous studies in Iran 10,19e21 as well as many other developing countries.…”

Prevalent Phenotypic and Genotypic Profile of Enterotoxigenic Escherichia coli among Iranian Children

“…The referenced studies indicated a higher frequency of ST-ETEC in Latin America/ the Caribbean, the Middle East/North Africa, and South Asia. In Iran, Katouli et al showed that ST was the most frequent toxin type (60z) followed by LT/ST and LT (20). Samples collected in 1998 showed a prevalence of the LT type (36).…”

“…Gupta et al highlighted a need for more information on the distribution of ETEC phenotypes (18). The role of ETEC in diarrhea1 disease in Iran has not been widely studied (19)(20)(21). Hence, the present study was designed to characterize the phenotypes and genotypes of ETEC associated with diarrhea among Iranian children aged less than 5 years.…”

Clonal groups of enteropathogenic Escherichia coli isolated in case-control studies of diarrhoea in Bangladesh

“…Similarities between the strains were calculated as correlation coefficients as described before [21] and clustered according to the unweighted pair group method with arithmetic averages (UPGMA) [22] yielding a dendrogram. An identity level of 0.975 was set based on reproducibility of the system as described before [23]. Strains showing similarities to each other higher than this value were regarded as identical and assigned to the same PhP types and those not identical to any other isolates were called single (Si) PhP types.…”