The role of long non-coding RNAs in carbohydrate and fat metabolism in the liver

The role of lncRNA-mediated ceRNA regulatory networks in liver fibrosis

“…In the context of competing endogenous RNAs (ceRNAs), lncRNAs contribute to extensive regulatory networks spanning the transcriptome, substantially expanding the functional genetic information encoded in the human genome. This diversified group of molecules plays a pivotal role in various pathological conditions [ [23] , [24] , [25] , [26] , [27] , [28] ] ( Fig. 1 ).…”

HOXC Cluster Antisense RNA 3, a Novel Long Non-Coding RNA as an Oncological Biomarker and Therapeutic Target in Human Malignancies

“…[1][2][3][4] Dysregulation of lncRNAs has been implicated in disease onset and progression, and their functional investigations have unveiled their essential role in various molecular processes, including cell growth, cell cycle, autophagy, [5][6][7] and metabolism. [8][9][10] Consequently, lncRNAs have emerged as novel disease targets for clinical applications, driven by an increased indepth understanding of their functions and molecular mechanisms.…”