2021
DOI: 10.7759/cureus.19158
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The Role of MicroRNA 181d as a Possible Biomarker Associated With Tumor Progression in Meningiomas

Abstract: Introduction Meningiomas are slow-growing intracranial neoplasms that originate from arachnoid meningothelial cells and represent 13-26% of intracranial tumors, thus being the most common. There are numerous technological advances available for a better understanding of the molecular pathways correlated with tumorigenesis and tumor progression of meningiomas. In this context, the role of microRNAs (miRNAs), which are non-coding RNAs (ncRNAs) consisting of 18 to 25 nucleotides whose function is the s… Show more

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Cited by 10 publications
(9 citation statements)
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“…Another aspect to be explored in the veterinary field is the challenge in classifying and diagnosing animal meningiomas [387][388][389]. The WHO classification of meningiomas acknowledges similarities across the three species but also differences.…”
Section: Discussionmentioning
confidence: 99%
“…Another aspect to be explored in the veterinary field is the challenge in classifying and diagnosing animal meningiomas [387][388][389]. The WHO classification of meningiomas acknowledges similarities across the three species but also differences.…”
Section: Discussionmentioning
confidence: 99%
“…Carneiro et al are exploring the potential role of miRNAs as biomarkers in the context of meningiomas, which are common intracranial tumors derived from arachnoid meningothelial cells [ 48 ]. Meningiomas constitute a significant percentage of intracranial tumors, making them a subject of significant clinical interest.…”
Section: Prospective Role Of Mirnas As Indicators and Targets For The...mentioning
confidence: 99%
“…Meningiomas constitute a significant percentage of intracranial tumors, making them a subject of significant clinical interest. The study focused on three specific miRNAs: miR-181 d, miR-181c and miR-130a, assessing their tissue and plasma expression in patients with different grades of meningioma [ 48 ]. The selection of these miRNAs is based on previous large-scale microarray analysis, reflecting the continuity and progress of research.…”
Section: Prospective Role Of Mirnas As Indicators and Targets For The...mentioning
confidence: 99%
“…A rise in miR-181d levels in both tumor tissue and plasma of meningioma patients significantly correlated with increasing pathological grade, with a more pronounced miR-181d upsurge seen in the latter sample type. 75 …”
Section: Biomarker Potential Of Mirnas In Meningiomamentioning
confidence: 99%