The Role of Psa, Digital Rectal Examination and Transrectal Ultrasonography in Diagnosis of Prostatic Cancer

Abstract

This study was held in Gaziantep University, School of Medicine, Department of Urology in the period of December 1992 through December 1996. Two group of patients have been included to the study; 30 prostate carcinoma and 30 benign prostate hyperplasia. Serum PSA levels werefound 10 times higher in prostate carcinoma group than BPH group. There was no statistically significant dijference between age and digital rectal examination finding with serum PSA levels of patients in both groups. Serum PSA levels and transrectal ultrasonography findings were comparedfor both group. No significant diference found between serum PSA levels and transrectal ultrasonography findings in BPH group. However, there has been statistically significant dijferences in prostate carcinoma group. When serum PSA levels and clinical stage with Gleason grade compared in prostate carcinoma group, statistically signifıcant difference was found. Although reserches are still continue to try to find the ideal test for diagnosing prostate cancer, serum PSA level is the most important parameter in early diagnosis. in this study we conclude that annual checking of serum PSA levels must be made for males over the age 50 and if it's more than 4 ng/ml, transrectal ultrasonography and biopsy must be peıformed.