The shape of things to come. Mapping spatiotemporal progression of striatal morphology in Huntington disease: The IMAGE-HD study

Wilkes, Fiona A.; Jakabek, David; Walterfang, Mark; Velakoulis, Dennis; Poudel, Govinda R.; Stout, Julie C.; Chua, Phyllis; Egan, Gary F.; Looi, Jeffrey C.L.; Georgiou-Karistianis, Nellie

doi:10.1016/j.pscychresns.2023.111717

Psychiatry Research: Neuroimaging

2023

DOI: 10.1016/j.pscychresns.2023.111717

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The shape of things to come. Mapping spatiotemporal progression of striatal morphology in Huntington disease: The IMAGE-HD study

Fiona A. Wilkes,

David Jakabek,

Mark Walterfang

et al.

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2024

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Bridging Huntington’s disease research with big data science: Harmonized neuroimaging datasets from multiple studies

Pustina,

Das,

Rozelle

et al. 2024

Imaging Neuroscience

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Multiple neuroimaging datasets from Huntington’s disease (HD) studies are publicly available, but these datasets are in various formats, omit imaging metadata, and sometimes contain corrupt scans. We have created a platform to curate, harmonize, and distribute neuroimaging datasets from eight different studies: TRACK-HD, TRACKOn-HD, PREDICT-HD, IMAGE-HD, HD-YAS, SHIELD-HD, PEARL-HD, and LONGPDE10. The platform is organized into three conceptual levels to serve the research community with both raw and processed data. Raw data are converted into Brain Imaging Data Structure (BIDS) format, while processed data are obtained from pipelines such as Freesurfer and fmriprep. Studies that had followed the same participants were combined. After combining studies, the final six BIDS datasets include a total of 2,216 participants and 7,073 sessions. We outline tools, principles, and recommendations for future data management in HD research.

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Bridging Huntington’s disease research with big data science: Harmonized neuroimaging datasets from multiple studies

Pustina,

Das,

Rozelle

et al. 2024

Imaging Neuroscience

View full text Add to dashboard Cite

show abstract

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The shape of things to come. Mapping spatiotemporal progression of striatal morphology in Huntington disease: The IMAGE-HD study

Cited by 1 publication

References 42 publications

Bridging Huntington’s disease research with big data science: Harmonized neuroimaging datasets from multiple studies

Bridging Huntington’s disease research with big data science: Harmonized neuroimaging datasets from multiple studies

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