The short pulse carbon dioxide laser versus the colorado needle tip with electrocautery for upper and lower eyelid blepharoplasty

Abstract

Neutrophil functions can be modified by Recombinant human G‐CSF (rhG‐CSF) treatment, with divergent effects on phagocytosis, motility, bactericidal activity, and surface molecule expression. Neutrophil morphology is modified by treatment with filgrastim (the nonglycosylated form of rhG‐CSF), while it is not affected by lenograstim (the glycosylated type of rhG‐CSF). Little information is available about actin polymerization in neutrophils from subjects treated with the two types of rhG‐CSF. In the current paper we evaluated two groups of donors of peripheral blood stem cells (PBSC) for allogeneic transplantation. Ten subjects were treated with filgrastim and 10 with lenograstim to mobilize PBSC; 15 blood donors were evaluated as a control group. Actin polymerization (both spontaneous and fMLP‐stimulated) was studied by a flow cytometric assay. A microscopic fluorescent assay was also carried out to evaluate F‐actin distribution in neutrophils. We found that filgrastim induced an increased F‐actin content in resting neutrophils, along with morphologic evidence for increased actin polymerization distributed principally at the cell membrane and frequently polarized in focal areas; in addition, fMLP was not able to induce further actin polymerization. On the contrary, treatment with lenograstim was associated with F‐actin content, distribution, and polymerization kinetics indistinguishable from those displayed by control neutrophils. Such experimental results show that filgrastim and lenograstim display divergent effects also on neutrophil actin polymerization and provide further explanation for previous experimental findings. Am. J. Hematol. 81:318–323, 2006. © 2006 Wiley‐Liss, Inc.

Long-Term Cicatrization Analysis in Periocular Incisions for Oculoplastic Surgery Performed With Cold Blade and Colorado Needle

“…Three previous studies have compared these 2 techniques in an area with different skin, as in the scalp. 5 The purpose of this study was to compare the degree of satisfaction of patients and observers about periocular scars secondary to skin incisions in oculoplastic surgery performed with cold blade versus Colorado microcautery needle. 1 On the other, the remaining 2 studies were not able to find statistically significant differences in the esthetic result of the scar after neurosurgical interventions.…”

Mid-Infrared Laser Orbital Septal Tightening

“…However, they are typically used as incisional or hemostatic devices aimed at replacing blades or electrocautery, with the goal of decreasing bruising or improving hemostasis. 15,16 The carbon dioxide laser is the most commonly used laser in blepharoplasty—primarily as a cutting instrument, although other lasers, such as the neodinium:YAG (Nd:YAG) and erbium: YAG (Er:YAG), have been used as well. 17 Prado et al 18 compared the use of the carbon dioxide laser to needle tip electrocautery in septal tightening in a fashion similar to that described by Cook et al 11 For the lower eyelid, a skin-muscle flap was raised and the electrocautery was applied in a grid-like fashion on one side and the carbon dioxide laser on the contralateral side.…”

Longitudinally Excited CO2 Laser

“…At present, a CO2 laser of about 3 W a pulsed CW of (10 -1000 ms and a super pulse of 0.1 -1 ms) is used for the skin treatment such as eliminating a mole, a wart, macule (Gotkin et al, 2009) and wrinkle the aurinasal treatment such as hay fever and allergic rhinitis (Takeno et al, 2009), the eye treatment such as blepharochalasis and droopy eyelid (Rokhsar et al, 2008), and the dental treatment such as section and evaporation of soft tissue, hemostasis, and stomatitis (Zand et al, 2009). The advantages of CO2 laser surgery are alleviation of bleeding, pain and edema, and shortening of operation and recovery time.…”