2024
DOI: 10.1113/ep092328
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The skeletal muscle proteomic determinants of neuromuscular function in young and older women following 8 weeks of resistance training

Mary O'Leary,
Elsa Greed,
Jack Pritchard
et al.

Abstract: Resistance training (RT) is the gold standard intervention for ameliorating sarcopenia. Outstanding mechanistic questions remain regarding the malleability of the molecular determinants of skeletal muscle function in older age. Discovery of proteomics can expand such knowledge. We aimed to compare the effect of RT on the skeletal muscle proteome and neuromuscular function (NMF) in older and younger women. Seven young (22 ± 6 years) and eight older (63 ± 5 years) women completed 8 weeks’ leg RT. Pre‐ and post‐t… Show more

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