The Solvent Influence on Thymidine-SDS-Alcohol Micelle System: Studies With UV-Vis Technique

Abstract

Vis technique are reported. The solvents selected were the following aliphatic alcohols: ethanol, n-butanol, n-heptanol and n-decanol. In this paper first time are presented data for SDS micelles in alcohols with some addition of water. In all studied systems concentrations of SDS (sodium dodecyl sulphate) were above CMC. Water concentration in the studied systems was defined by R parameter according to relation: R=[H 2 O]/[AOT] and was between 0 to 50 depending on the system. In the present work SDS micelles mimicked in a very simple way the structural aspects of some domain in bio membranes. The distribution of thymidine, which is one of the pyrimidine bases of living matter (is found in the nucleic acid DNA) between organic and micellar phase was the object of our study. Using UV-Vis technique the investigation of thymidine/alcohol/SDS/water system at 25°C were done, and next the results were discussed in the context of influence an aliphatic alcohol on thymidine interaction with SDS micelles. Moreover, obtained results involve us to predict the privilege location of thymidine molecules in SDS micelles. The experimental values of thymidine absorbance as a function of surfactant Wachnik et al.