The Spatial Dynamics of Poliomyelitis in the United States: From Epidemic Emergence to Vaccine-Induced Retreat, 1910–1971

Abstract

This article seeks to advance an understanding of the spatial dynamics of one of the great emergent viral diseases of the twentieth century-poliomyelitis.

Historic Disease Data as Epidemiological Resource: Searching for the Origin and Local Basic Reproduction Number of the 1878 Yellow Fever Epidemic in Memphis, Tennessee

“…For example, Smallman-Raynor and Cliff (2001) identified diffusion processes of typhoid in the dynamic environment of military encampments, and Curtis, Mills, and Blackburn (2007) and Curtis (2008) discovered the spatiotemporal patterns of yellow fever transmission in the 1878 epidemic in New Orleans, including the existence of cultural clustering of the disease. Trevelyan, Smallman-Raynor, and Cliff (2005) revealed the changing spatial patterns of poliomyelitis from its emergence in the United States to its decline in the face of vaccination. Cliff and Haggett (2006) implemented a swash-backwash model to understand the spatial distribution of measles in Iceland with implications for broader use.…”

Live Attenuated Vaccines for the Immunoprophylaxis

“…Эпидемические вспышки полиомиелита, ко ри, краснухи, эпидемического паротита и брюш-ного тифа, прокатившиеся по странам Европы и Северной Америки во второй половине ХХ в. определили развитие работ по созданию эффек-тивных и безопасных вакцин [4,23,45,78]. Уже к концу 60-х -началу 70-х гг.…”

O início do fim da poliomielite: 60 anos do desenvolvimento da vacina

“…Apenas nos Estados Unidos, mais de 20.000 casos de poliomielite paralítica foram notificados anualmente durante a década de 1950. Após o licenciamento da vacina inativada entre os anos de 1955 a 1961, mais de 300 milhões de doses da vacina foram administradas, levando a uma redução de 90% na incidência da poliomielite 5,6 .…”