1992
DOI: 10.1002/art.1780351115
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The spectrum of pericardial tamponade in systemic lupus erythematosus: Report of ten patients

Abstract: Objective. To describe the range of clinical manifestations and the outcome of pericardial tamponade in patients with systemic lupus erythematosus (SLE).Methods. Patients with pericarditis and with pericardial tamponade were identified from our computerized database of 395 SLE patients. Medical records were reviewed to establish activity of SLE at the time of tamponade, as well as clinical and laboratory features, treatment, and outcome of the tamponade.Results. Pericarditis occurred in 75 patients (19%), with… Show more

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Cited by 83 publications
(62 citation statements)
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“…The reported prevalence of pericardial effusions/pericarditis in SLE ranges from 9 to 58% on echocardiographic studies, and is usually asymptomatic and associated with active disease. 32,33 Pericardial tamponade is rare; 34,35 and while our patient had echocardiographic evidence of tamponade, she was managed expectantly given the absence of clinical hemodynamic compromise. Serosal disease in SLE usually responds to immunosuppressive therapy, as occurred in our patient after auto-HSCT.…”
Section: Discussionmentioning
confidence: 80%
“…The reported prevalence of pericardial effusions/pericarditis in SLE ranges from 9 to 58% on echocardiographic studies, and is usually asymptomatic and associated with active disease. 32,33 Pericardial tamponade is rare; 34,35 and while our patient had echocardiographic evidence of tamponade, she was managed expectantly given the absence of clinical hemodynamic compromise. Serosal disease in SLE usually responds to immunosuppressive therapy, as occurred in our patient after auto-HSCT.…”
Section: Discussionmentioning
confidence: 80%
“…One reason tamponade is so rare may be that many people are diagnosed and treated earlier due to other presenting symptoms before tamponade occurs. Interestingly presenting with tamponade tends to be more likely in women and in individuals with higher ESR values, lower C4 levels, concurrent renal disease and pleurisy, all of which were present in our patient [3][4][5].…”
Section: To the Editormentioning
confidence: 74%
“…Pericarditis is a frequent cardiac manifestation of systemic lupus erythematosus (50-62%) but tamponade -although classical-is scarcely reported (1%) [1,2] .…”
Section: Case Reportmentioning
confidence: 99%