Detecting active black holes in dwarf galaxies has proven to be a challenge due to their small size and weak electromagnetic signatures. Mid-infrared variability has emerged as a promising tool that can be used to detect active low-mass black holes in dwarf galaxies. We analyzed 10.4 yr of photometry from the AllWISE/NEOWISE multiepoch catalogs, identifying 25 objects with active galactic nuclei (AGN)-like variability. Independent confirmation of AGN activity was found in 68% of these objects using optical and near-infrared diagnostics. Notably, we discover a near-infrared coronal line [S ix] λ 1.252 μm in J1205, the galaxy with the lowest stellar mass (log M
* = 7.5 M
⊙) and low metallicity (12 + log(O/H) = 7.46) in our sample. Additionally, we find broad Paα potentially from the broad-line region in two targets, and their implied black hole masses are consistent with black hole-stellar mass relations. Comparing nonvariable galaxies with similar stellar masses and Wide-field Infrared Survey Explorer W1 − W2 colors, we find no clear trends between variability and large-scale galaxy properties. However, we find that AGN activity likely causes redder W1 − W2 colors in variable targets, while for the nonvariable galaxies, the contribution stems from strong star formation activity. A high incidence of optical broad lines was also observed in variable targets. Our results suggest that mid-infrared variability is an effective method for detecting AGN activity in low-mass galaxies and can help uncover a larger sample of active low-mass (<106
M
⊙) black holes in the Universe.