The structure of calenduloside A

Vecherko, L. P.; Zinkevich, E. P.; Libizov, N. I.; Ban'kovskii, A. I.

doi:10.1007/bf01032018

Cited by 5 publications

(3 citation statements)

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“…The therapeutic effects of the C. officinalis is caused by a significant group of secondary metabolites called terpenoids. 1,8,41 Various terpenoids isolated (Figure 2) are calenduladiol-3-O-palmitate, stigmasterol, lupeol, Ψ-taraxasteol, 42 8,43 calendulosides A-H, 8,37,44 and calendulaglycoside A and B. 27,45…”

Section: Terpenoidsmentioning

confidence: 99%

A Review on Traditional Uses, Phytochemistry and Pharmacological Activities of Calendula officinalis Linn

Sapkota,

Kunwar

2024

Natural Product Communications

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Calendula officinalis Linn, known as pot marigold, is a plant that belongs to the Asteraceae family. Various online bibliographic databases namely, Google scholar, PubMed, SciFinder, and Web of Science were used for integrating information. Calendula officinalis is extensively used in Homoeopathic, Unani, and Ayurvedic system of medication as diaphoretic, analgesic, antiseptic, and anti-inflammatory agents and used to treat gynaecological issues, gastro-intestinal disorders, inflammations of oral and pharyangeal mucosa, eye problems, skin injuries and certain burns, poor eyesight, and menstrual irregularities. Several studies have shown that Calendula officinalis is a major source of diverse classes of bioactive compounds namely terpenoids, flavonoids, coumarines, quinones, and carotenoids. Various in vivo and in vitro assessment of Calendula officinalis's pharmacological activity suggest that the plant has antidiabetic, anti-inflammatory, anti-tumor, anticancer, and gastroprotective activity. This review compiles the information about pharmacological activities, traditional medicinal uses, and phytochemicals present in Calendula officinalis.

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Section: Terpenoidsmentioning

confidence: 99%

A Review on Traditional Uses, Phytochemistry and Pharmacological Activities of Calendula officinalis Linn

Sapkota,

Kunwar

2024

Natural Product Communications

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“…In addition to oleanolic acid, β-sitosterol and salvigenin, which have been previously isolated from the plant [9c], the triterpenoids 3-formyl-ursolic acid, 20 2α,3β,23-trihydroxyurs-12-en-28-oic acid (asiatic acid), 21 3- O -β-galactopyranosyloleanolic acid, 22 betulinic acid, 23 the steroidal compound daucosterol, 24 the flavonoid apigenin-7- O -glucoside, 25 the phenyl ethanoid 2-(4-hydroxyphenethyl) tetratriacontanoate, 26 and the phenolic compound rosmarinic acid 27 were isolated and are described here from S. hydrangea for the first time.…”

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confidence: 99%

Chemical Constituents From the Ethyl Acetate Extract of Salvia hydrangea

Kahnamoei

Tabefam

Ebrahimi

et al. 2019

Natural Product Communications

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One new triterpenoid, 3β-O-(2-hydroxybenzoyl)-ursolic acid (1), and 11 known compounds, including 5 triterpenoids, 2 steroidal compounds, and 4 phenolic compounds were isolated from the ethyl acetate extract of the aerial parts of Salvia hydrangea. Their structures were elucidated based on the extensive spectroscopic data, including 1-dimensional and 2-dimensional nuclear magnetic resonance spectra, high resolution-electrospray ionization mass spectrometry, and by comparison with literature data. The antiprotozoal activity of compound 1 was evaluated against Trypanosoma brucei rhodesiense, Trypanosoma cruzi, Leishmania donovani, Plasmodium falciparum and showed no activities against all parasite tested.

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“…The remaining three saponins (D2, C, and A) were the 28^-D-glucopyranosyl ester of glycosides F, D, and B, respectively. However, among these proposed structures, only those of glycosides F and D2 were clearly established by comparison with calenduloside F (6).…”

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confidence: 99%