2016
DOI: 10.18410/jebmh/2016/632
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The Study of Clinical Variations and Histopathological Findings in Polymorphous Light Eruption

Abstract: BACKGROUND Epstein. S in 1942 described PMLE under the name of Prurigo aestivalis. He first hypothesised that PMLE represents a form of delayed-type hypersensitivity response to an endogenous, cutaneous UV-induced antigen, because of the hours or days delay between sun exposure and manifestation of symptoms, and the histological appearance of lesional skin. Firm evidence; however, has been lacking and the responsible allergen has not been identified. PMLE a specific entity encompassing six clinical manifestati… Show more

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Cited by 1 publication
(3 citation statements)
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“…[ 19 20 21 22 ] The possible mechanisms involved in pathogenesis are given in the form of a chart [ Figure 1 ] which incorporates various factors involved. [ 23 24 25 26 27 ]…”
Section: Pathogenesis Of Pmlementioning
confidence: 99%
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“…[ 19 20 21 22 ] The possible mechanisms involved in pathogenesis are given in the form of a chart [ Figure 1 ] which incorporates various factors involved. [ 23 24 25 26 27 ]…”
Section: Pathogenesis Of Pmlementioning
confidence: 99%
“…The action spectrum involves UVA, UVB, and visible light. [ 25 36 ] There is also an interesting observation of PMLE preferentially involving the sites of hypopigmented scars. [ 37 ]…”
Section: Clinical Featuresmentioning
confidence: 99%
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