The Study of Physical and Chemical Properties of Water-Soluble Polymer Reagents and Their Compatibility With Antibiotics

Dzhakipbekov, Erzhan; Sakibayeva, Saule; Dzhakipbekova, Nagima; Tarlanova, Botagoz; Sagitova, G.F.; Shingisbayeva, Zhadra

doi:10.31788/rjc.2020.1325709

Cited by 3 publications

(2 citation statements)

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“…Most antibiotics that can be hydrolyzed are water-soluble and the degree of hydrolysis is dependent on the specific characteristics of antibiotics [ 70 ]. Tetracycline, β-lactams, and macrolides are relatively easily hydrolyzed [ 71 , 72 , 73 , 74 , 75 ] while quinolones and sulfonamides are not [ 76 , 77 ].…”

Section: Degradation Of Antibiotics In the Natural Environmentmentioning

confidence: 99%

Current Progress in Natural Degradation and Enhanced Removal Techniques of Antibiotics in the Environment: A Review

Zheng

Wang

Chen

et al. 2022

IJERPH

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Antibiotics are used extensively throughout the world and their presence in the environment has caused serious pollution. This review summarizes natural methods and enhanced technologies that have been developed for antibiotic degradation. In the natural environment, antibiotics can be degraded by photolysis, hydrolysis, and biodegradation, but the rate and extent of degradation are limited. Recently, developed enhanced techniques utilize biological, chemical, or physicochemical principles for antibiotic removal. These techniques include traditional biological methods, adsorption methods, membrane treatment, advanced oxidation processes (AOPs), constructed wetlands (CWs), microalgae treatment, and microbial electrochemical systems (such as microbial fuel cells, MFCs). These techniques have both advantages and disadvantages and, to overcome disadvantages associated with individual techniques, hybrid techniques have been developed and have shown significant potential for antibiotic removal. Hybrids include combinations of the electrochemical method with AOPs, CWs with MFCs, microalgal treatment with activated sludge, and AOPs with MFCs. Considering the complexity of antibiotic pollution and the characteristics of currently used removal technologies, it is apparent that hybrid methods are better choices for dealing with antibiotic contaminants.

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Section: Degradation Of Antibiotics In the Natural Environmentmentioning

confidence: 99%

Current Progress in Natural Degradation and Enhanced Removal Techniques of Antibiotics in the Environment: A Review

Zheng

Wang

Chen

et al. 2022

IJERPH

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“…The kinematic viscosity of 0.1% aqueous solution is not less than (1.7 ± 2) 10 -6 . 2,3 WATER SOLUTIONS OF POLYMERS E. Dzhakipbekov et al…”

Section: Polyacrylamide (Paa)mentioning

confidence: 99%

Untitled

2021

RJC

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In this article are shown soft dosage forms (ointments) obtained based on polymer reagents. Water-soluble polymers are synthesized based on acryl-containing compounds. Aqueous solutions of polymeric reagents and their physical and chemical properties (viscosity and optical density) have been investigated. It was shown that polymers can be used for the transportation of drugs. The polymer macromolecule at pH = 3.5 is in a folded state. The macromolecule is unfolded with increasing pH. This leads to an increase in viscosity, the optical density does not change. The drugs are passed toxicological control. Based on toxicological investigate and analysis of the data obtained, it was concluded that the polymers have insignificant functional accumulation. Do not show skinresorptive and allergic effects. The compatibility of polymers with antibiotics (levomycetin, levomycetin sodium succinate) was investigated. To establish the compatibility of copolymers with the antibiotics levomycetin, levomycetin sodium succinate and neomycin sulfate, it is necessary to identify the antimicrobial activity of antibiotics, which is determined by diffusion into agar. The properties of soft dosage forms (ointments) were sinvestigated using the agar diffusion method, it was shown that antibiotics are compatible in combination with the polymer reagent and their antimicrobial activity was revealed.

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Synthesis of EPAN and applications in the encapsulation of potassium humate

Smailov,

Aravind,

Kadirbayeva

et al. 2024

Green Processing and Synthesis

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This article provides information on the synthesis of esterified derivatives of hydrolyzed polyacrylonitrile (EPAN) based on the polymer waste “Nitron” for use as an encapsulating reagent. The elemental and structural compositions of potassium humate and the organic polymer were determined using a scanning electron microscope (Jeol JSM-6490l V) and an IR Fourier spectrometer (Zhimadzu IR Prestige-21). A method is presented for determining the strength of the encapsulated granules of potassium humates using an IPG-1M device and a TAXTplus texture analyzer (Stable Microsystems). The scientific novelty of the article lies in the synthesis of EPAN from “Nitron” polymer waste using sodium hydroxide in the presence of ethylene glycol at a temperature of 370 K for 4 h, followed by the use of 0.5% synthesized solution for encapsulating the granular potassium humate produced from humic acid to give a strength of up to 17.3 kg and prolonged action to the granules. The effect of EPAN concentration on the encapsulation process of granular potassium humates was investigated and studied. The mechanism for the formation of a protective layer of granular potassium humates in the form of a transparent film has been established. The results of the experimental work were processed using the integrated program Statistica-10, which showed a 3D simulation of the process. Microscopic, IR spectral, X-ray phase and thermogravimetric analyses of the encapsulated potassium humate were carried out using modern instrumental devices (MicroXRF Analysis Report, monochromator D878-PC75-17.0, TGA/DSC 1HT/319). The encapsulated durable potassium humate granules provide longer-term nutrition, i.e., a slow, gradual release of plant nutrients in the soil. The use of the produced high-strength encapsulated potassium humate granules allows for restoring soil fertility and increasing the yield of agricultural plants. The encapsulated granules can withstand numerous transshipments and long-term transportation while maintaining the commercial and consumer properties of the product.

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The Study of Physical and Chemical Properties of Water-Soluble Polymer Reagents and Their Compatibility With Antibiotics

Cited by 3 publications

References 0 publications

Current Progress in Natural Degradation and Enhanced Removal Techniques of Antibiotics in the Environment: A Review

Current Progress in Natural Degradation and Enhanced Removal Techniques of Antibiotics in the Environment: A Review

Untitled

Synthesis of EPAN and applications in the encapsulation of potassium humate

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