The study of stereoselectivity and mesomeric effect of N-nitrosamines via 1H NMR spectroscopy

Abstract

Nano-kaolin-SO 3 H was prepared and used to synthesis of N-nitrosamines. The products were characterized by their spectral (IR and 1 H NMR) data. N-nitrosamines can exist in two mesomeric forms but the reaction is quite regioselective and only one of mesomers is formed as main product which can exist in two E and Z stereoisomers. In this paper, we have studied the mesomeric effect of N-nitrosamines which explained the diastereotopic nature of corresponding protons in symmetric N-nitrosamines and formation of two isomers in asymmetric N-nitrosamines.