Tawes (Barbonymus gonionotus) is a type of endemic fish that lives in the Boon Pring Reservoir, Turen, and Malang Regency. This study aims to analyze the water quality and blood profile of Tawes Fish (Barbonymus gonionotus) in Boon Pring Ecotourism and to determine the relationship between water quality and fish health through their blood profile using the Canonical Correspondence Analysis (CCA) method. The results obtained after measuring the water quality during two samplings at both locations were that the temperature ranged from 21.7–27C, TDS 111–145 mg/l, TSS 2-4 mg/l, pH 6-6.7, DO 8–10.1 mg/l, BOD 0.44-0.98 mg/l, and ammonia 0.026–0.075 mg/l. Both locations are classified as having good or normal conditions. Observations on the blood profile of Tawes fish (Barbonymus gonionotus) are healthy and normal. The average number of erythrocytes was 2,586,667 cells/mm3, leukocytes were 60,500 cells/mm3, lymphocytes were 76.8%, monocytes were 1.4%, neutrophils were 3.3%, hemoglobin was 9.8 g/mL, hematocrit was 34.6%, and micronuclei were 12.3 cells/1000. The results of data analysis using CCA showed that all blood and micronuclei profiles of fish were affected by water quality parameters, both significantly and moderately to severely.