The Top 50 Most Cited Articles in Cartilage Regeneration

Donald, Ciaran K Mc; Moriarty, Peter; Varzgalis, Manvydas; Murphy, Colin G.

doi:10.1089/biores.2017.0006

Cited by 9 publications

(21 citation statements)

References 55 publications

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“…It can be seen from basic science data that the overall majority of the work undertaken by the science community at present was to (a) investigate the outcome of enhanced tissue scaffolding to regenerate articular cartilage and (b) investigate the usage of mesenchymal stem cells to help regenerate articular cartilage 38…”

Section: Discussionmentioning

confidence: 99%

“…Several papers have come up recently in the most influential publications in the field of science,2 various medical specialties,3456789101112131415 and orthopedics in particular 161718. Soon after Lefaivre et al 16 published their article on the top 100 most-cited papers in orthopedics, numerous papers depicting the most-cited articles in different orthopedic subspecialties,1920212223242526272829303132333435 related to specific disorders36373839 and publication trends from different countries,4041424344 have appeared. Such reviews provide a useful reference for research quality and evolution of practice, areas of controversy, and future research goals in a particular field.…”

Section: Introductionmentioning

confidence: 99%

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The Upsurge in Research and Publication on Articular Cartilage Repair in the Last 10 Years

Vaishya

Patralekh

Vaish

2019

IJOO

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This study aims to study the publication trends in articular cartilage repair (ACR) techniques, over the last 10 years. A literature search was performed on the PubMed, Web of Science, and SCOPUS databases. We used suitable keywords and Boolean operators (articular cartilage injury AND “marrow stimulation OR microfracture (MFx),” “osteochondral autograft,” “osteochondral allograft” and “autologous chondrocyte implantation (ACI),” “scaffold”), on January 1, 2019. Trends in publication on these topics were analyzed, focusing on publications over the last 10 years, type of research, authors, institution, and country. There was an increasing trend in publications related to ACR. A search on PubMed revealed 698, 225, 293, 857, and 982 documents on searching for “articular cartilage” AND “marrow stimulation OR microfracture,” “osteochondral autograft,” “osteochondral allograft,” “ACI,” and “scaffold,” respectively. Similar searches revealed 1154, 219, 330, 1727, and 2742 documents on Web of science and 934, 301, 383, 944, and 2026 on SCOPUS, respectively, in the same order of topics. Overall, most papers were published from the United States and European countries, and Cole BJ was the most published author. There was an increasing trend in the number of publications as well as citations, with international collaboration among researchers. It implies that this field is growing rapidly. The authors from globally recognized and leading clinical institutions in the developed world contributed maximally to these publications. Most of these papers were published in high-impact arthroscopy subspecialty journals. Level of evidence: Level IV.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

The Upsurge in Research and Publication on Articular Cartilage Repair in the Last 10 Years

Vaishya

Patralekh

Vaish

2019

IJOO

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“…When chondrocytes are cultured in vitro, they will gradually dedifferentiate as the number of culture passages increases, losing the unique phenotype of chondrocytes. The tissue obtained by expansion of such dedifferentiated chondrocytes is usually fibrocartilage [ 21 ]. The normal articular cartilage in the body is hyaline cartilage tissue, which is composed of mature cartilage cells with a good phenotype and the extracellular matrix secreted by them [ 22 ].…”

Section: Analysis Of Osteoarticular Cartilage Regenerationmentioning

confidence: 99%

Stem Cells Promote the Regeneration of Knee Joint Degenerative Bone and Articular Cartilage

Zheng

2022

Journal of Healthcare Engineering

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Cartilage damage has a certain ability to spontaneously repair, but the repaired tissue often shows the phenomenon of cartilage terminal differentiation, which causes irreversible damage to its structure and function and seriously affects the quality of life and work of patients. It is of great significance to study the problems encountered in the process of cartilage damage repair. This article mainly studied stem cells to promote the regeneration of knee joint degenerative bone articular cartilage. First, the animal articular cartilage defect is modeled, 10 ml of animal venous blood is drawn, 0.5 ml of PRP is collected by centrifugation, mixed with cartilage fragments, and transplanted into the defect area into a gel. In the BMSCs group, 1 ml of BMSCs with a cell concentration of 107 cells/ml was injected intra-articularly. The histological chromosomes were observed after 6 weeks and 12 weeks, and the effect of cartilage tissue repair was analyzed and evaluated, and the related data were statistically analyzed. We evaluated the spontaneous repair ability of partial cartilage damage, full-thickness cartilage damage, and osteochondral damage. Furthermore, for partial cartilage damage repair, by using the cartilage damage in vitro model and biomaterials to simulate the in vivo microenvironment, the adhesion and cell morphology on the surface of partial- and full-thickness cartilage damage were evaluated, and the experiments were further used to evaluate the exogenous and internal induced migration effect of source on cultured cells in vitro. In the cell concentration study, the cartilage repair effect increased with the increase in concentration within a certain range, and the tissue repair ability remained stable when the concentration exceeded 107 cells/ml. Using ECM-oriented scaffolds to compound autologous BMSCs, tissue-engineered cartilage was successfully constructed, which had the histological and biochemical characteristics of normal cartilage tissue, and better repaired the damaged articular cartilage of large animals.

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“…Unlike traditional citation counts, a bibliometric approach considers the connections within the literature; notably, it identifies intellectual structures and emerging trends (8). Within the field of tissue regeneration, bibliometric analyses have been employed to estimate its research trends, including cardiac (9), neural (10), periodontal (11), cartilage (12), and bone regeneration (13). However, no bibliometric reports assessing the relevant scientific outputs and research trends of studies on skin regeneration have yet been published.…”

Section: Introductionmentioning

confidence: 99%

Deciphering the focuses and trends in skin regeneration research through bibliometric analyses

Zhou

Chen²,

Shu³

et al. 2022

Front. Med.

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Increasing attention to skin regeneration has rapidly broadened research on the topic. However, no bibliometric analysis of the field’s research trends has yet been conducted. In response to this research gap, this study analyzed the publication patterns and progress of skin regeneration research worldwide using a bibliometric analysis of 1,471 papers comprising 1,227 (83.4%) original articles and 244 (16.6%) reviews sourced from a Web of Science search. Publication distribution was analyzed by country/region, institution, journal, and author. The frequency of keywords was assessed to prepare a bibliometric map of the development trends in skin regeneration research. China and the United States were the most productive countries in the field: China had the greatest number of publications at 433 (29.4%) and the United States had the highest H-index ranking (59 with 15,373 citations or 31.9%). Author keywords were classified into four clusters: stem cell, biomaterial, tissue engineering, and wound dressing. “Stem cells,” “chitosan,” “tissue engineering,” and “wound dressings” were the most frequent keywords in each cluster; therefore, they reflected the field’s current focus areas. “Immunomodulation,” “aloe vera,” “extracellular vesicles,” “injectable hydrogel,” and “three-dimensional (3D) bioprinting” were relatively new keywords, indicating that biomaterials for skin regeneration and 3D bioprinting are promising research hotspots in the field. Moreover, clinical studies on new dressings and techniques to accelerate skin regeneration deserve more attention. By uncovering current and future research hotspots, this analysis offers insights that may be useful for both new and experienced scholars striving to expand research and innovation in the field of skin regeneration.

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The Top 50 Most Cited Articles in Cartilage Regeneration

Cited by 9 publications

References 55 publications

The Upsurge in Research and Publication on Articular Cartilage Repair in the Last 10 Years

The Upsurge in Research and Publication on Articular Cartilage Repair in the Last 10 Years

Stem Cells Promote the Regeneration of Knee Joint Degenerative Bone and Articular Cartilage

Deciphering the focuses and trends in skin regeneration research through bibliometric analyses

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