The treatment of allergic rhinitis in asthmatic children and adolescents: practical outcomes from the real-world “ControL’Asma” study

Tosca, Maria Angela; Marseglia, Gian Luigi; Ciprandi, Giorgio; Anastasio, Elisa; Brambilla, Ilaria; Caffarelli, Carlo; Chini, L; Ciprandi, Riccardo; Vittori, Valentina De; Duse, Marzia; Cicco, Maria Di; Indinnimeo, Luciana; Kantar, Ahmad; Leone, Massimo; Licari, Amelia; Marinelli, Guido; Moschese, Viviana; Olcese, Roberta; Peroni, Diego; Pistorio, M. A.; Salmaso, C.; Silvestri, Michela; Zicari, Anna Maria

doi:10.23822/eurannaci.1764-1489.171

Cited by 4 publications

(4 citation statements)

References 13 publications

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“…are exposed to the allergen. 18 When individual remain unguarded to allergen mostly airborne dust, faeces of mite, cockroach residue, mould, pollens, food, and animal hackles then IgE is secreted by plasma which initiates the release of cysteinyl leukotrienes, prostaglandin D2 and histamine etc. This release is responsible for triple response (dilation of arteriole, flare and increase of vascular permeability) and for critical characteristics of AR which is itching, runny nose, red eyes, sneezing, nasal pruritus, air flow obstruction, blockage and mucous secretion.…”

Section: Pathophysiologymentioning

confidence: 99%

Levo Cetirizine - the Drug with Numerous Plus to Cure Allergic Syndrome Compared to other Treatment Systems

Upasana¹,

Sunil²,

Bharkatiya³

2022

JOPCR

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Many drugs are available to treat allergic condition. This review focused on why antihistaminics are best choice for treatment of allergic disorder especially allergic rhinitis (AR). AR is a chronic inflammatory disease. AR can be detected by its characteristics of nasal congestion, nasal itching, sneezing, rhinorrhoea, pruritis, redness, tearing and itching of eyes. This is very common and increases day after day. Allergic rhinitis is not lethal but interferes with daily schedule in a sustained manner. It is also observed that after COVID-19, stimuli reactions such as allergic condition, breathing difficulties and nasal irritation are quite common. It is very necessary to treat AR with an effective and powerful medicine because nowadays, many factors trigger these responses such as the environment, food products, pollution, etc. Before treatment of any symptoms it is very necessary to know it pathogenesis. Hence, in this review, we discuss the introduction of AR, its pathogenesis, diagnostics, classification and treatment. We also understand why levocetirizine, a third-generation antihistamine, is superior to all other antihistamines and the most favourable in paediatric patients in many ways. Keywords: Allergic rhinitis, Antihistaminic, Levocetirizine, COVID19, Asthma, Nasal congestion

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Section: Pathophysiologymentioning

confidence: 99%

Levo Cetirizine - the Drug with Numerous Plus to Cure Allergic Syndrome Compared to other Treatment Systems

Upasana¹,

Sunil²,

Bharkatiya³

2022

JOPCR

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“…A real-world survey of children treated for allergic rhinitis revealed 37.9% had mild intermittent AR, 9.2% moderate/severe intermittent AR, 47.6% mild persistent AR and 5.2% moderate/severe persistent AR. 6 The survey reported that 75% chose pharmacotherapy and only 19.5% opted for allergen immunotherapy. Notably, oral antihistamines were the predominant treatment in 57.6%, intranasal corticosteroids (INCS) in 53%, and combined oral antihistamines with INCS in 35.0% of patients.…”

Section: Introductionmentioning

confidence: 99%

“…Notably, oral antihistamines were the predominant treatment in 57.6%, intranasal corticosteroids (INCS) in 53%, and combined oral antihistamines with INCS in 35.0% of patients. 6 This emphasizes the role of pharmacotherapy as the mainstay treatment for the different types and severity of AR. As all pharmacotherapy is safe at the recommended dose, the treatment can be given as long as it is required.…”

Section: Introductionmentioning

confidence: 99%

Pharmacological Management of Allergic Rhinitis: A Consensus Statement from the Malaysian Society of Allergy and Immunology

Abdullah¹,

Latiff²,

Manuel³

et al. 2022

JAA

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The goal of allergic rhinitis (AR) management is to achieve satisfactory symptom control to ensure good quality of life. Most patients with AR are currently treated with pharmacotherapy. However, knowledge gaps on the use of pharmacotherapy still exist among physicians, particularly in the primary care setting, despite the availability of guideline recommendations. Furthermore, it is common for physicians in the secondary care setting to express uncertainty regarding the use of new combination therapies like intranasal corticosteroid plus antihistamine combinations. Inadequate treatment leads to significant reduction of quality of life that affects daily activities at home, work, and school. With these concerns in mind, a practical consensus statement was developed to complement existing guidelines on the rational use of pharmacotherapy in both the primary and secondary care settings.

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“…e common treatment methods of Western medicine are hormone therapy, antihistamine therapy, and immunotherapy, which can obtain certain curative effect, but it has some side effects, drug dependence, and easy recurrence [3]. e long-term effect is not good, and there is a certain degree of nephrotoxicity; the disease cannot be cured as a whole [4]. erefore, in order to make the curative effect lasting and effective, actively looking for the exact treatment plan has far-reaching social significance.…”

Section: Introductionmentioning

confidence: 99%

Effect of Medicine‐Separated Moxibustion on Navel Combined with Mind‐Regulating Acupuncture on Curative Effect and Quality of Life in Patients with Allergic Rhinitis

Zhang

Wang

2022

Contrast Media & Molecular Imaging

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Objective. To explore the effect of medicine-separated moxibustion combined with mind-regulating acupuncture on the efficacy and quality of life of patients with allergic rhinitis (AR). Methods. Sixty patients with AR cured from February 2019 to April 2021 were enrolled in our hospital. The patients were arbitrarily assigned into control and study groups. The former group was treated with herbal moxibustion on the navel, while the latter group was treated with herbal moxibustion on the navel combined with mind-regulating acupuncture. The curative effect, TNSS score, TNNSS score, RQLQ score, and the incidence of adverse events were compared. Results. Compared with the two groups, the study group was markedly effective in 24 cases, effective in 5 cases, and ineffective in 1 case, with an effective rate of 100.00%, while the control group was markedly effective in 13 cases, effective in 10 cases, and ineffective in 7 cases, with an effective rate of 100.00%. The curative effect of the study group was better compared to the control group (P < 0.05). There was no remarkable difference in TNSS score before treatment (P > 0.05). After treatment, the TNSS scores of patients decreased. Compared with the control group, the TNSS score of the study group was lower than that of the control group at 2 weeks, 4 weeks and during the follow-up. No remarkable difference appeared in the TNNSS score before treatment (P > 0.05). After treatment, the TNNSS scores of patients were decreased. Comparing the two groups, the TNNSS scores of the study group were lower compared to the control group after 2 weeks of treatment, 4 weeks of treatment and during the follow-up period (P < 0.05). There was no remarkable difference in the RQLQ score before treatment (P > 0.05). After treatment, the RQLQ scores of patients were decreased. Comparing the two groups, the RQLQ scores of the study group were lower compared to the control group at 2 weeks, 4 weeks after treatment and during the follow-up period (P < 0.05). In terms of the incidence of adverse events, the incidence of adverse events such as subcutaneous hematoma, bruising, and induration in the study group was lower compared to the control group (P < 0.05). Conclusion. Medicine-separated moxibustion was combined with mind-regulating acupuncture when treating AR. There were differences in clinical efficacy, single-symptom score, and TNSS, TNNSS, and RQLQ scores, which verified the clinical efficacy of medicine-separated moxibustion combined with mind-regulating acupuncture when treating AR, and expounded the mechanism of medicine-separated moxibustion combined with mind-regulating acupuncture when treating AR. In the meantime, it shows that the umbilical method of medicine-separated moxibustion combined with mind-regulating acupuncture when treating AR has the advantages of definite short-term effect, long-term effect, safe and simple operation, and no adverse reactions, which is worthy of clinical application.

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The treatment of allergic rhinitis in asthmatic children and adolescents: practical outcomes from the real-world “ControL’Asma” study

Cited by 4 publications

References 13 publications

Levo Cetirizine - the Drug with Numerous Plus to Cure Allergic Syndrome Compared to other Treatment Systems

Levo Cetirizine - the Drug with Numerous Plus to Cure Allergic Syndrome Compared to other Treatment Systems

Pharmacological Management of Allergic Rhinitis: A Consensus Statement from the Malaysian Society of Allergy and Immunology

Effect of Medicine‐Separated Moxibustion on Navel Combined with Mind‐Regulating Acupuncture on Curative Effect and Quality of Life in Patients with Allergic Rhinitis

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