The Vagal Body and Its Tumour

Abstract

To a philosopher, no circumstance, however trifling, INCE the first recognition of the carotid S body by von Haller in 1743, a number of other small masses of similar tissue has been described and the known branohial glomera or, as they are commonly described to-day, non-chromaffin paraganglia may be enumerated thus :2. The vagal bodyparaganglion juxtaor intra-vagale-situated in, or in juxtaposition with, the vagus nerve at the level of, or immediately below, the ganglion nodosum. The carotid body.4. The aortic bodies one of which is situated at the junction of the innominate and right subclavian arteries and the other at the junction of the aorta and left subclavian arteries. These bodies were described first by Muratori (1934) in animals and named the aortic glomi by Nonidez ( 1935).5. The pulmonary bodies, the superior body being found in the angle between the pulmonary artery and the left coronary artery, whilst the inferior body is found between the aortic arch and the ductus arteriosus. These bodies were fully described first by Palme (1934) as the paraganglia supracardiule superius et inferius.Recently, Barnard (1946) has described another paraganglion, which is constant in its situation, in this area between the pulmonary artery and the ductus arteriosus. is too minute."Goldsmith:

Intra and juxtavagal paraganglia: A topographical, histochemical, and ultrastructural study in the human

“…The most inferior localization reported by this author was 2.0 cm below the lower border of the inferior vagal ganglion. In each of the 4 temporal bones sectioned through the superior vagal ganglion, Birrel (1953) found vagal bodies in the adventitia of the jugular bulb and within the ganglion itself. Among sensory ganglia, vagal ganglia are unique in containing paraganglionic tissue.…”

“…In humans, vagal glomi have been recognized in the superior and inferior vagal ganglia and within or adjacent to the first centimeters of the nerve trunk immediately distal to the inferior ganglion (White, 1935;Lattes, 1950; Set0 et al, 1950;Hermann, 1951;Watzka and Scharf, 1951;Birrel, 1953; Lack, 1978). The description of a few vagal paraganglioma inferior to the carotid bifurcation in humans (Marcuse and Chamberlin, 1956;Jernstrom and Fry, 1957;Carey and Bradley, 1963) raises the question of a more extensive distribution along this nerve.…”

Tumor multifocality with vagus nerve involvement as a phenotypic marker of SDHD mutation in patients with head and neck paragangliomas: A 18F‐FDOPA PET/CT study

“…5 Stout identified the first paraganglioma of the vagus nerve, 24 and Birrell proposed the term vagal body tumor in 1953. 25 During the past decades, several case series have been reported VP with possible multifocality with other PGL and malignant potential. Its possible familial occurrence has been formally recognized after it has been made for carotid and jugular PGL.…”

The Jugular Body and Its Tumour

“…Other areas, particularly those deeper in the tumour, may show predominantly fibrous tissue (Fig. X)-a common finding in both the carotid and vagal body tumours (Birrell, 1952(Birrell, , 1953. Again…”

“…(Case 1 1 ) . (~3 8 0 ) Attempts were made with the material available, to demonstrate a "nerve supply" similar to that found in the carotid body tumour (Birrell, 1952). Some success has been achieved using Willis's (1954) been demonstrated, despite the close resemblance of the parenchyma of the tumour to It should be noted here that distant the normal body's parenchyma; previous experience has shown that one needs a fortunate section for this purpose.…”