“…An appropriate mixed dentition space analysis (MDS) helps to reduce the severity of a developing malocclusion or even eliminate it, if timely interceptive treatment is initiated (Moyers, 1988;Kuswandari et al, 2006). An accurate forecast of the size of unerupted teeth versus the available space helps orthodontists to make correct decisions regarding treatment options for the patient, whether to involve serial extraction, eruption guidance, space management, space regaining or just periodic observation of the patient (Hukaba, 1964;Smith et al, 1979;Bishara and Jakobsen, 1998;Lee-Chan et al, 1998;Luu et al, 2011). Inappropriate and invalid MDS can lead to extraction decisions, which negatively alters a patient's soft tissue facial profile (Durgekar and Naik, 2009), dental aesthetics and functional occlusion.…”