The Weiss Ring, a Major Confounding Factor For Measurements of Peripapillary Retinal Nerve Fiber Layer Thickness

Lee, Min‐Woo; Kim, Minsu; Yu, Hwa-Young; Park, Kee-Sup; Lee, Young Hoon; Kim, Jung‐Yeul

doi:10.1016/j.ajo.2022.01.001

Cited by 1 publication

(1 citation statement)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Because Weiss ring can be located in front of the optic disc, we hypothesized that it may affect pRNFL thickness measurements obtained using SD-OCT. In our previous study 14 , we found that inferior and average pRNFL were thinner in eyes with Weiss ring than in eyes without Weiss ring. However, since pRNFL thickness can vary from patient to patient, our colleagues thought that it would be more meaningful to analyze the agreement and difference of pRNFL thickness measurements at two consecutive visits in the same patients.…”

Section: Introductionmentioning

confidence: 59%

Effect of Weiss ring on peripapillary retinal nerve fiber layer thickness measurements using SD-OCT

Kim

Nam

Hwang

et al. 2022

Sci Rep

Self Cite

View full text Add to dashboard Cite

Spectral-domain optical coherence tomography (SD-OCT) must accurately identify and measure the peripapillary retinal nerve fiber layer (pRNFL) thickness to improve the repeatability and reproducibility, and reduce measurement errors. Because Weiss ring can be located in front of the optic disc, we hypothesized that it may affect pRNFL thickness measurements obtained using SD-OCT. We retrospectively reviewed the medical records of patients with (group W) and without (group N) Weiss ring, observed on OCT fundus image and an RNFL map devised using SD-OCT. Optic disc cube scans (200 × 200) were obtained to measure pRNFL thicknesses (superior, temporal, inferior, nasal, and average) at two consecutive visits. Pearson's correlation coefficient (r), intraclass correlation coefficient (ICC), and coefficient of variation (CV) were calculated. The r and ICC values for the pRNFL thickness measurements at the two visits were lower for group W compared to group N, but statistical significance was reached only for inferior pRNFL thickness. In addition, CV values were greater for group W compared to group N, but the differences were significant only for inferior and average pRNFL thickness measurements (p < 0.001 and p = 0.004, respectively). Weiss ring located near the optic disc can affect pRNFL thickness measurements and repeatability thereof, especially the inferior quadrant and average values. Therefore, it is important to identify the presence of Weiss ring when analyzing pRNFL thickness values.

show abstract

Section: Introductionmentioning

confidence: 59%