The WISDOM study pilot: Evaluating a preference-tolerant RCT of risk-based vs. annual breast cancer screening.

Theiner, S; Kaplan, Celia P.; Sarrafan, S; Cabrera, Julissa; Sawyer, Sarah; Liang, April S.; Rosenberg-Wohl, Sarah; Frick, Miya; Wong, Emily; Tice, Jeffrey A.; Ziv, Elad; Borowsky, Alexander D.; Anton‐Culver, Hoda; Naeim, Arash; LaCroix, Andrea Z.; Cink, Thomas M.; Esserman, Laura J.; Veer, Laura van’t; Fiscalini, Allison Stover

doi:10.1200/jco.2016.34.15_suppl.e13035

Cited by 2 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In a computational model, a risk-stratified screening program was more effective in terms of reducing interval cancers and false positive screens than the existing system based only on age and gender (23). International studies undertaken in United States (13), United Kingdom (24), and the Netherlands (25) have demonstrated acceptability of risk-stratified screening programs, however Australian women's attitudes are unknown.…”

Section: Introductionmentioning

confidence: 97%

“…There is a growing interest in risk-stratified population breast screening (9,(12)(13)(14)(15)(16)(17), due to the robust evidence of the skewed distribution of breast cancer risk in the population (18). For example, based on polygenic risk estimates, women in the highest centile have an estimated absolute lifetime risk of developing breast cancer by the age of 80 of 33% compared with only 3% for women in the lowest risk centile (19).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

“A Natural Progression”: Australian Women's Attitudes About an Individualized Breast Screening Model

Lippey

Keogh

Mann

et al. 2019

Cancer Prevention Research

100

View full text Add to dashboard Cite

Individualized screening is our logical next step to improve population breast cancer screening in Australia. To explore breast screening participants' views of the current program in Victoria, Australia, examine their openness to change, and attitudes toward an individualized screening model, this qualitative work was performed from a population-based breast screening cohort. This work was designed to inform the development of a decision aid to facilitate women's decisions about participating in individualized screening, and to elicit Australian consumer perspectives on the international movement toward individualized breast screening. A total of 52 women participated in one of four focus groups, and were experienced with screening with 90% of participants having had more than three mammograms. Focus group discussion was facilitated following three main themes: (i) experience of breast screening; (ii) breast cancer risk perception, and (iii) views on individualized screening. Participants had strong, positive, emotional ties to breast screening in its current structure but were supportive, with some reservations, of the idea of individualized screening. There was good understanding about the factors contributing to personalized risk and a wide range of opinions about the inclusion of genetic testing with genetic testing being considered a foreign and evolving domain. Individualized breast screening that takes account of risk factors such as mammographic density, lifestyle, and genetic factors would be acceptable to a population of women who are invested in the current system. The communication and implementation of a new program would be critical to its acceptance and potential success. Reservations may be had in regards to uptake of genetic testing, motivations behind the change, and management of the women allocated to a lower risk category.

show abstract