Themes that Determine Quality of Life in Patients with Peripheral Arterial Disease: A Systematic Review

Aber, Ahmed; Lumley, Elizabeth; Phillips, Patrick J.; Woods, Helen Buckley; Jones, Georgina; Michaels, Jonathan

doi:10.1007/s40271-018-0307-7

Cited by 28 publications

(32 citation statements)

References 21 publications

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“…( 1 , 2 , 3 , 4 ) Currently, there is a tendency in increasing the number of patients with symptomatic PAD which is associated with "rejuvenation" Atherosclerosis of the lower extremities a r t e r i e s h a v e t e n d e n c y t o c o n s t a n t progression, frequent amputation and disability, high lethality, which is associated with huge economic costs . (5,6,7) In recent decades, the study of the quality of (8,9) i n t e g r a l h e a l t As expected, the stress severity levels recorded were moderate for stages IIA, IIB and III and extremely severe in the terminal stage ( Figure 2b).…”

Section: Introductionsupporting

confidence: 57%

Beyond the Arteries in Peripheral Artery Disease

et al. 2018

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Objectives. This study aimed to examine peripheral artery disease severity impact on psychological profile of arteriopathy patients.Material and methods. The prospective study included consecutive PAD patients admitted to the 2nd Department of Internal Medicine and the Department of Cardiology of the Emergency Clinical Hospital “Sf. Spiridon” Iasi, between January and September, 2017.Rezults. The group included 139 PAD patients, 80.6% male and 19.4% female, with an average age of 63.23±9.44 years. PAD stages have a very strong association with level of quality of life (p<0.0001). All Leriche-Fontaine classification categories were significantly associated with the depressive symptoms (p<0.0001). The stress level was moderate in stages IIA, IIB and III and extremely severe in the terminal stage. The prevalence of anxiety was lowest in incipient PADstages with the highest value in stage III.Conclusions. The fragment of the PhD study presented the psychological profile in the PAD staging and advocates a personalized, wide-ranging approach to the arteriopathy patient including pain and depressive-anxiety management, with amajor impact on the quality of life at terminal stages.

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Section: Introductionsupporting

confidence: 57%

Beyond the Arteries in Peripheral Artery Disease

et al. 2018

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“…3 Items were developed based on themes extracted from primary qualitative data, systematic qualitative evidence synthesis and clinicians' consensus exercise. [9][10][11][12][13] We have made efforts through purposive sampling to ensure that we have included diverse demographic groupings in the primary research, and this is augmented by the inclusion of systematic reviews that include evidence gathered in national and international studies. Another strength of this study is that the qualitative evidence in the review and the primary study included patients at different stages of their disease.…”

Section: Discussionmentioning

confidence: 99%

“…4-8 3. Developing the items within each section of ePAQ-VAS based on qualitative systematic reviews [9][10][11][12] and a primary qualitative study. 13…”

Section: Open Accessmentioning

confidence: 99%

Mixed methods study to develop the content validity and the conceptual framework of the electronic patient-reported outcome measure for vascular conditions

et al. 2020

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ObjectiveThe aim of this paper is to describe the stages undertaken to generate the items and conceptual framework of a new electronic personal assessment questionnaire for vascular conditions.DesignA mixed methods study: First a survey of vascular clinicians was completed to identify the most common conditions treated in vascular clinics and wards. Quantitative systematic reviews were done to identify validated patient-reported outcome measures (PROMs) for direct inclsuion in the new instrument. However, due to scarcity of validated PROMs, the items of the new instrument were mainly based on a large qualitative study of patients and systematic reviews of the qualitative evidence . This was followed by a quantitative clinicians’ consensus study and, finally, a qualitative face validity study with patients.ParticipantsVascular patients participated in the primary qualitative study and the face validity study. In the qualitative study, 55 patients were interviewed, and for the face validity, 19 patients gave feedback. Twelve clinicians completed the survey and 13 completed two cycles of the clinicians’ consensus study.ResultsThe items and scales in the electronic personal assessment questionnaire for vascular conditions (ePAQ-VAS) were generated based on the results of five systematic reviews evaluating existing PROMs for possible inclusion in ePAQ-VAS, five systematic reviews of qualitative evidence, a primary qualitative study involving 55 patients and clinicians’ input. One hundred and sixty-eight items were initially generated, of which 59 were eliminated by the expert panel due to repetition. The instrument was divided into one generic and three disease-specific sections (abdominal aortic aneurysm, carotid artery disease and lower limb vascular conditions). In each section, items were grouped together into putative scales. Fifty-five items were grouped across eight scales; the remaining items were kept as individual items, because of relevance to service users.ConclusionsThis multidimensional electronic questionnaire covers the most common vascular conditions. This is particularly important for patients presenting with mixed symptoms or multiple conditions. This tool captures symptomatology, health related quality of life (HRQoL) and other clinically relevant data, such as experience with services and comorbidities.

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“…The conceptual framework for the ePAQ‐VAS questionnaire was developed from three distinct sources to identify the key issues, symptoms and impact of AAA, PAD, CAD, VLU and VV on patients with these conditions. First, systematic literature reviews of existing outcome measures and qualitative evidence were conducted. Second, clinicians involved in the care of vascular patients were invited to list the key issues, symptoms and impact of these conditions.…”

Section: Methodsmentioning

confidence: 99%

Electronic personal assessment questionnaire for vascular conditions (ePAQ-VAS): development and validity

Aber

Phillips

Hughes

et al. 2020

British Journal of Surgery

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Background This paper describes the development and validation of an electronic personal assessment questionnaire for vascular conditions (ePAQ‐VAS) that captures the symptomatology, quality of life and clinically relevant data of patients presenting to vascular services. Methods A two‐stage survey was conducted in patients attending a tertiary vascular department. Patients completed the ePAQ‐VAS remotely online, or on site using an electronic tablet. In the first stage of the survey, the responses were used to perform confirmatory factor analysis to assess the construct validity and remove redundant items. The internal reliability of disease‐specific scales was investigated. In the second stage of the survey, the acceptability, known‐group validity, test–retest reliability, and responsiveness of ePAQ‐VAS was assessed. Results In total, 721 patients completed ePAQ‐VAS. Their mean(s.d.) age was 63·5(15·7) years and 468 (64·9 per cent) were men. Some 553 patients (76·7 per cent) completed the questionnaire in clinic and the remainder completed the questionnaire online. The results of the confirmatory factor analysis confirmed the conceptual model for ePAQ‐VAS structure and eliminated six items. Internal reliability was acceptable for all the scales (Cronbach's α greater than 0·7). The test–retest reliability measured by the intraclass correlation coefficient ranged from 0·65 to 0·99. The results showed that the instrument was responsive over time with the standardized response mean ranging from 0·69 to 1·60. Conclusion ePAQ‐VAS is a holistic data‐collection process that is relevant to vascular service users and has potential to contribute to patient‐focused care and the collection of aggregate data for service evaluation. A demonstration version of the final version of ePAQ can be viewed at http://demo-questionnaire.epaq.co.uk/home/project?id=VASC_1.7&page=1.

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Themes that Determine Quality of Life in Patients with Peripheral Arterial Disease: A Systematic Review

Cited by 28 publications

References 21 publications

Beyond the Arteries in Peripheral Artery Disease

Beyond the Arteries in Peripheral Artery Disease

Mixed methods study to develop the content validity and the conceptual framework of the electronic patient-reported outcome measure for vascular conditions

Electronic personal assessment questionnaire for vascular conditions (ePAQ-VAS): development and validity

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