Theoretical and solid-state structures of three new macroacyclic Schiff base complexes and the investigation of their anticancer, antioxidant and antibacterial properties

Abstract

Symmetrical macroacyclic Schiff base complexes were prepared from a ligand derived from the condensation reaction of 1,4-bis(2-aminophenyl)piperazine and salicylaldehyde (L) with Co(ii) perchlorates.

Anticancer, antioxidant, and antimicrobial studies and molecular docking of a new hexanuclear Zn(ii) complex, together with its X-ray crystal analysis

“…Apparently, the alteration in the nature of the metal ion and coordination sites affects the biological activity by changing the binding ability of DNA. 56–60…”

“…Apparently, the alteration in the nature of the metal ion and coordination sites affects the biological activity by changing the binding ability of DNA. [56][57][58][59][60] 4. Conclusion In order to assess the potential biological effects of these compounds, an array of investigations encompassing molecular docking, anticancer, antibacterial, and antioxidant activities were carried out.…”