2022
DOI: 10.1002/jca.22034
|View full text |Cite
|
Sign up to set email alerts
|

Therapeutic plasma exchange for steroid refractory idiopathic inflammatory myopathies with interstitial lung disease

Abstract: Background Idiopathic inflammatory myopathies (IIMs) encompass many rheumatologic diseases characterized by inflammatory muscle disease, typically unified by proximal muscle weakness. A subset of patients with IIM present with interstitial lung disease (ILD) with identifiable antibodies such as in anti‐synthetase syndrome (AS) with antibodies to aminoacyl‐tRNA synthetases, and clinically amyopathic dermatomyositis (CADM) with anti‐melanoma differentiation‐associated protein 5 (MDA5). Recent case reports demons… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1

Citation Types

0
4
0

Year Published

2023
2023
2024
2024

Publication Types

Select...
4

Relationship

0
4

Authors

Journals

citations
Cited by 4 publications
(4 citation statements)
references
References 44 publications
0
4
0
Order By: Relevance
“…The overwhelming majority of the data are for its use in clinically amyopathic DM and specifically anti-MDA5 disease. 188,189 However, there are case reports [190][191][192] and one case series 193 showing favorable outcomes in those with ASyS-ILD. Other therapies that have been trialed for IIM-ILD include antitumor necrosis factor-α, 194,195 tocilizumab, [196][197][198] and anakinra.…”
Section: Other Therapiesmentioning
confidence: 99%
“…The overwhelming majority of the data are for its use in clinically amyopathic DM and specifically anti-MDA5 disease. 188,189 However, there are case reports [190][191][192] and one case series 193 showing favorable outcomes in those with ASyS-ILD. Other therapies that have been trialed for IIM-ILD include antitumor necrosis factor-α, 194,195 tocilizumab, [196][197][198] and anakinra.…”
Section: Other Therapiesmentioning
confidence: 99%
“…Therapeutic Apheresis Apheresis involves the extracorporeal removal, return, or exchange of large substances from the blood or plasma. Two case reports have demonstrated its use in ASyS refractory to steroids and other therapeutic agents [143,144]. 9.9.2.…”
Section: Intravenous Immunoglobulinmentioning
confidence: 99%
“…Although there is biologic plausibility for the treatment of IIM-ILD/AS-ILD or anti-MDA5+ ILD with IVIG and PEX, there is limited evidence [62–64]. However, they may have less risk of infection compared with other regimens.…”
Section: Treatmentmentioning
confidence: 99%
“…Although there is biologic plausibility for the treatment of IIM-ILD/AS-ILD or anti-MDA5þ ILD with IVIG and PEX, there is limited evidence [62][63][64].…”
Section: Intravenous Immunoglobulin and Plasma Exchangementioning
confidence: 99%