Thermal Flow Sensors for Very Small Flow Rate

The authors report on the concept and development of an intelligent intraoral drug delivery microsystem, that provides an alternative approach for the treatment of addiction and chronic diseases. The drug delivery system (DDS) comprises a medication replacement reservoir, a medication release mechanism, a built-in intelligence, a remote control, microsensors, and microactuators. It is thus able to release the medication in a controlled manner according to the patient needs. The emphasis of this article is on the application of sensors and microfluidic components in a real microsystem and also showing some details of two system components, namely, the osmotic pump and the flow sensor. The motivation for the microfluidic approach, the concept of the DDS, the requirements for this specific application, and the arising problems will be presented and discussed. Regarding the sensors and actuators, the problems mainly concern size and power consumption. A major challenging aspect of microfluidic component development is to avoid clogging of small channels because of particles and recrystallization of saturated fluids

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“…Ashauer et al [8], for example, report on such a sensor, that is based on a thermotransfer measuring principle.…”

Section: Flow Sensormentioning

confidence: 98%

Intelligent intraoral drug delivery microsystem

Velten

Schuck

Knoll

et al. 2006

Proceedings of the Institution of Mechanical Engineers, Part C:

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“…1. The channel fabrication is performed by a double KOH etching process (DKOH) at the back side of our standard flow sensor chip [10]. Fig.…”

Section: Realizationmentioning

confidence: 99%

Monolithic integration of micro-channel on disposable flow sensors for medical applications

Billat

Kliche

Gronmaier

et al. 2008

Sensors and Actuators A: Physical

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“…For example an extension of the membrane from 300 µm to 380 µm width induces a sensitivity increase of about 40% in air for a 1 mm! channel cross section in case of our standard flow sensor [10]. Furthermore free degree of channel design is given by RIE etching which allows the realization of meanders for the fluid channel on an optimized reduced silicon area.…”

Section: Realisationmentioning

confidence: 99%